Catalog No.
YHK66201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr276-Thr342
Predicted molecular weight
20.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NYD6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HOX3I, Homeobox protein Hox-C10, Homeobox protein Hox-3I, HOXC10
Innovating Glioma Therapy Using Secretions from Umbilical Cord Mesenchymal Stem Cells to Target Homeobox and Growth Factor Genes., PMID:40421391
Circ-ITCH promotes the ubiquitination degradation of HOXC10 to facilitate osteogenic differentiation in disuse osteoporosis through stabilizing BRCA1 mRNA via IGF2BP2-mediated m6A modification., PMID:40148953
Identification of Deregulated miRNAs and mRNAs Involved in Tumorigenesis and Detection of Glioblastoma Patients Applying Next-Generation RNA Sequencing., PMID:40143207
Skin regional specification and higher-order HoxC regulation., PMID:40117347
Mechanism of RBM15 in the malignant proliferation of colorectal cancer cells through regulating the stability of LncRNA FGD5-AS1 via m6A modification., PMID:39701357
HOXA7 Expression Is an Independent Prognostic Biomarker in Esophageal Squamous Cell Carcinoma., PMID:39596630
Hoxc10-mediated 'positional memory' regulates cartilage formation subsequent to femoral heterotopic grafting., PMID:39434203
The HOXC10/NOD1/ERK axis drives osteolytic bone metastasis of pan-KRAS-mutant lung cancer., PMID:39191757
HOXC10 promotes hypertrophic scar fibroblast fibrosis through the regulation of STMN2 and the TGF-β/Smad signaling pathway., PMID:39152325
Genomic characterization of cervical lymph node metastases in papillary thyroid carcinoma following the Chornobyl accident., PMID:38871684
Heterozygous deletion of HOXC10-HOXC9 causes lower limb abnormalities in congenital vertical talus., PMID:38296636
Pan-cancer analysis of homeodomain-containing gene C10 and its carcinogenesis in lung adenocarcinoma., PMID:38154103
m6A‑modified HOXC10 promotes HNSCC progression via co‑activation of ADAM17/EGFR and Wnt/β‑catenin signaling., PMID:38063205
Silencing HOXC13 exerts anti-prostate cancer effects by inducing DNA damage and activating cGAS/STING/IRF3 pathway., PMID:38057852
Comprehensive Multiomics Analyses Establish the Optimal Prognostic Model for Resectable Gastric Cancer : Prognosis Prediction for Resectable GC., PMID:37996637
KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster., PMID:37861717
Analysis of Zinc and Stromal Immunity in Disuse Osteoporosis: Mendelian Randomization and Transcriptomic Analysis., PMID:37752822
KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster., PMID:37577627
HOTAIR as a diagnostic and prognostic biomarker of gastrointestinal cancers: an updated meta-analysis and bioinformatics analysis based on TCGA data., PMID:36924407
Expression Profiles, Prognosis, and ceRNA Regulation of SRY-Related HMG-Box Genes in Stomach Adenocarcinoma., PMID:36749091
Genome-wide methylation profiling identify hypermethylated HOXL subclass genes as potential markers for esophageal squamous cell carcinoma detection., PMID:36447287
HOXC10 indicates poor survival outcome in gastric cancer and promotes G1/S cell cycle transition through transcriptional repression of p21., PMID:36264773
Prokineticins as a Prognostic Biomarker for Low-Grade Gliomas: A Study Based on The Cancer Genome Atlas Data., PMID:35845958
Histone methyltransferase DOT1L is essential for self-renewal of germline stem cells., PMID:35738678
Identification of HOX signatures contributing to oral cancer phenotype., PMID:35710803
Identification of Crucial lncRNAs for Luminal A Breast Cancer through RNA Sequencing., PMID:35692369
[The effect of HOXC10 gene on biological behaviors of glioma cells and mechanism in tumor microenvironment]., PMID:35316872
SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ., PMID:35196497
Homeodomain-containing gene 10 contributed to breast cancer malignant behaviors by activating Interleukin-6/Janus kinase 2/Signal transducer and activator of transcription 3 pathway., PMID:34983296
HOXC6/8/10/13 predict poor prognosis and associate with immune infiltrations in glioblastoma., PMID:34763232
Upregulation of HOX genes promotes cell migration and proliferation in head and neck squamous cell carcinoma., PMID:34633333
Transcription factor HOXC10 activates the expression of MTFR2 to regulate the proliferation, invasion and migration of colorectal cancer cells., PMID:34523692
Identification of cis-HOX-HOXC10 axis as a therapeutic target for colorectal tumor-initiating cells without APC mutations., PMID:34320348
The lncRNA HMS recruits RNA-binding protein HuR to stabilize the 3'-UTR of HOXC10 mRNA., PMID:34302808
HOXC10 Suppresses Browning to Maintain White Adipocyte Identity., PMID:33990396
In silico analysis of HOX-associated transcription factors as potential regulators of oral cancer., PMID:33741282
The crest phenotype in domestic chicken is caused by a 197 bp duplication in the intron of HOXC10., PMID:33704432
Homeobox A5 and C10 genes modulate adaptation of brown adipose tissue during exercise training in juvenile rats., PMID:33369800
Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p., PMID:33368224
Differential abilities to engage inaccessible chromatin diversify vertebrate Hox binding patterns., PMID:33028607
Low HOXC10 expression in liver cancer regulates proliferation via a mechanism involving miR-221 and the MAPK signaling pathway., PMID:32934696
HOXC10 upregulation confers resistance to chemoradiotherapy in ESCC tumor cells and predicts poor prognosis., PMID:32587398
MiR-129-5p Restrains Apatinib Resistance in Human Gastric Cancer Cells Via Downregulating HOXC10., PMID:32552008
MiR-129-5p induces cell cycle arrest through modulating HOXC10/Cyclin D1 to inhibit gastric cancer progression., PMID:32356314
A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers., PMID:32243838
Interleukin 1β-mediated HOXC10 Overexpression Promotes Hepatocellular Carcinoma Metastasis by Upregulating PDPK1 and VASP., PMID:32206125
Identification of key long non-coding RNAs in gastric adenocarcinoma., PMID:32176636
MircoRNA-129-5p suppresses the development of glioma by targeting HOXC10., PMID:32111444
HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells., PMID:31812713
A four-gene signature-derived risk score for glioblastoma: prospects for prognostic and response predictive analyses., PMID:31565488
For research use only. Not for human or drug use.
