Catalog No.
YHK66001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu15-Gln108
Predicted molecular weight
22.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BXL8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HEPP, Cell division cycle-associated protein 4, CDCA4, Hematopoietic progenitor protein
RAD51 expression and prognostic impact in patients with stomach adenocarcinoma., PMID:40231067
IGF2BP2-induced circRNF20 facilitates breast cancer cell proliferation via the HuR/CDCA4 axis., PMID:39969065
CDCA genes as prognostic and therapeutic targets in Colon adenocarcinoma., PMID:39924497
CDCA4 promotes bladder cancer progression by JAK/STAT signaling pathway., PMID:39856473
Hsa_circ_0087784 enhances non-small cell lung cancer progression via the miR-576-5p/CDCA4 axis., PMID:39278405
Comprehensive bioinformatics analysis and cell line experiments revealed the important role of CDCA3 in sarcoma., PMID:39035484
Predicting regulatory mutations and their target genes by new computational integrative analysis: A study of follicular lymphoma., PMID:38901187
CDCA gene family promotes progression and prognosis in lung adenocarcinoma., PMID:38875380
Exploring the role of CDCA4 in liver hepatocellular carcinoma using bioinformatics analysis and experiments., PMID:38701314
Integrated bioinformatics analysis and experimental validation identified CDCA families as prognostic biomarkers and sensitive indicators for rapamycin treatment of glioma., PMID:38181024
ALKBH5 promotes the development of lung adenocarcinoma by regulating the polarization of M2 macrophages through CDCA4., PMID:37949419
LINC00638/hsa-miR-29b-3p axis-mediated high expression of CDCA4 correlates with tumor immune infiltration and hepatocellular carcinoma progression., PMID:37304553
Ubiquitin-independent proteasomal degradation driven by C-degron pathways., PMID:37201526
CDCA4 interacts with IGF2BP1 to regulate lung adenocarcinoma proliferation via the PI3K/AKT pathway., PMID:36737405
STAT1 Mediates the Transcription of CircIFI30 and Promotes the Progression of Triple-Negative Breast Cancer by Up-Regulating CDCA4., PMID:35378000
Identification of a Tumor Cell Associated Type I IFN Resistance Gene Expression Signature of Human Melanoma, the Components of Which Have a Predictive Potential for Immunotherapy., PMID:35269844
A Pan-Cancer Analysis of the Oncogenic Role of Cell Division Cycle-Associated Protein 4 (CDCA4) in Human Tumors., PMID:35251007
CDCA1/2/3/5/7/8 as novel prognostic biomarkers and CDCA4/6 as potential targets for gastric cancer., PMID:35116645
Microribonucleic Acid-15a-5p Alters Adriamycin Resistance in Breast Cancer Cells by Targeting Cell Division Cycle-Associated Protein 4., PMID:34785950
MiR-497-5p down-regulates CDCA4 to restrains lung squamous cell carcinoma progression., PMID:34772428
Implications of cell division cycle associated 4 on the Wilm's tumor cells viability via AKT/mTOR signaling pathway., PMID:34723730
Upregulation of miR-29c-3p Hinders Melanoma Progression by Inhibiting CDCA4 Expression., PMID:34497853
Long non-coding RNA LINC01116 is activated by EGR1 and facilitates lung adenocarcinoma oncogenicity via targeting miR-744-5p/CDCA4 axis., PMID:34090440
Multidimensional study of cell division cycle-associated proteins with prognostic value in gastric carcinoma., PMID:34082692
PCOS follicular fluid derived exosomal miR-424-5p induces granulosa cells senescence by targeting CDCA4 expression., PMID:33930499
ELK1-induced upregulation lncRNA LINC02381 accelerates the osteosarcoma tumorigenesis through targeting CDCA4 via sponging miR-503-5p., PMID:33640603
Comprehensive Analysis of Aerobic Exercise-Related Genes Identifies CDCA4 That Promotes the Progression of Osteosarcoma., PMID:33613651
Integrate analysis of the promote function of Cell division cycle-associated protein family to pancreatic adenocarcinoma., PMID:33437202
CDCA4 suppresses epithelial-mesenchymal transtion (EMT) and metastasis in Non-small cell lung cancer through modulating autophagy., PMID:33436008
miRNA biomarkers for predicting overall survival outcomes for head and neck squamous cell carcinoma., PMID:33279650
Circ_0010220-mediated miR-503-5p/CDCA4 axis contributes to osteosarcoma progression tumorigenesis., PMID:32827680
Apelin enhances biological functions in lung cancer A549 cells by downregulating exosomal miR-15a-5p., PMID:32808032
A multidimensional systems biology analysis of cellular senescence in aging and disease., PMID:32264951
Knockdown of cell division cycle-associated protein 4 expression inhibits proliferation of triple negative breast cancer MDA-MB-231 cells in vitro and in vivo., PMID:30944632
CDCA4, a downstream gene of the Nrf2 signaling pathway, regulates cell proliferation and apoptosis in the MCF‑7/ADM human breast cancer cell line., PMID:29257222
MicroRNA-15a inhibits the growth and invasiveness of malignant melanoma and directly targets on CDCA4 gene., PMID:27492455
Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP., PMID:25691055
Differential expression of microRNAs in 2-cell and 4-cell mouse embryos., PMID:23731853
Clinical scale ex vivo manufacture of neutrophils from hematopoietic progenitor cells., PMID:19591208
Transcriptional co-factor CDCA4 participates in the regulation of JUN oncogene expression., PMID:18572021
The spindle function of CDCA4., PMID:18498124
Transcriptional and subcellular regulation of the TRIP-Br family., PMID:17141982
CDCA4 is an E2F transcription factor family-induced nuclear factor that regulates E2F-dependent transcriptional activation and cell proliferation., PMID:16984923
Evolutionary conservation and murine embryonic expression of the gene encoding the SERTA domain-containing protein CDCA4 (HEPP)., PMID:16546331
Cloning and characterization of Hepp, a novel gene expressed preferentially in hematopoietic progenitors and mature blood cells., PMID:11482882
For research use only. Not for human or drug use.
