Catalog No.
YHE51101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala286
Predicted molecular weight
35.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P47755
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
F-actin-capping protein subunit alpha-2, CAPZA2, CapZ alpha-2
Multiomics profiles of genome-wide alterations in H3K27ac in different lung lobes after acute graft-versus-host disease with MSCs treatment., PMID:40443676
Genomic insights into growth traits in German Black Pied cattle: a dual-purpose breed at risk., PMID:40424954
Exploring potential diagnostic markers and therapeutic targets for type 2 diabetes mellitus with major depressive disorder through bioinformatics and in vivo experiments., PMID:40369032
Heterozygous CAPZA2 mutations cause global developmental delay, hypotonia with epilepsy: a case report and the literature review., PMID:38374166
Comprehensive clinicopathological, molecular, and methylation analysis of mesenchymal tumors with NTRK and other kinase gene aberrations., PMID:38332737
SEPTIN10-mediated crosstalk between cytoskeletal networks controls mechanotransduction and oncogenic YAP/TAZ signaling., PMID:38242197
MET Fusions in NSCLC: Clinicopathologic Features and Response to MET Inhibition., PMID:37429463
MET gene alterations predict poor survival following chemotherapy in patients with advanced cancer., PMID:36483096
A de novo inframe deletion variant in CAPZA2 tentacle domain with global developmental delay and secondary microcephaly., PMID:35856264
Capping protein regulates endosomal trafficking by controlling F-actin density around endocytic vesicles and recruiting RAB5 effectors., PMID:34796874
The role of CAPG in molecular communication between the embryo and the uterine endometrium: Is its function conserved in species with different implantation strategies?, PMID:32619075
Cytoskeleton regulators CAPZA2 and INF2 associate with CFTR to control its plasma membrane levels under EPAC1 activation., PMID:32573649
Variants in CAPZA2, a member of an F-actin capping complex, cause intellectual disability and developmental delay., PMID:32338762
Molecular Profiling of Tumor Tissue and Plasma Cell-Free DNA from Patients with Non-Langerhans Cell Histiocytosis., PMID:31015311
Xiao-Xu-Ming decoction extract regulates differentially expressed proteins in the hippocampus after chronic cerebral hypoperfusion., PMID:30539815
Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus., PMID:29702546
Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion., PMID:28202517
Novel kinase fusion transcripts found in endometrial cancer., PMID:26689674
Inactivation of the paraoxonase 1 gene affects the expression of mouse brain proteins involved in neurodegeneration., PMID:24844689
Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration., PMID:24496069
Chronic phencyclidine increases synapsin-1 and synaptic adaptation proteins in the medial prefrontal cortex., PMID:23738220
Discovery and characterization of chromatin states for systematic annotation of the human genome., PMID:20657582
Molecular-assisted immunohistochemical optimization., PMID:19628254
Novel breast cancer biomarkers identified by integrative proteomic and gene expression mapping., PMID:18318472
WNT2B: comparative integromics and clinical applications (Review)., PMID:16273293
Extensive analysis of the 7q31 region in human prostate tumors supports TES as the best candidate tumor suppressor gene., PMID:15252854
V-1, a protein expressed transiently during murine cerebellar development, regulates actin polymerization via interaction with capping protein., PMID:12488317
An updated linkage and comparative map of porcine chromosome 18., PMID:11736809
Identification of an amplified gene cluster in glioma including two novel amplified genes isolated by exon trapping., PMID:9402967
Vertebrates have conserved capping protein alpha isoforms with specific expression patterns., PMID:9331217
Coordinated regulation of platelet actin filament barbed ends by gelsolin and capping protein., PMID:8707824
Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families., PMID:7665558
For research use only. Not for human or drug use.
