Catalog No.
YHD10301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp111-Leu513
Predicted molecular weight
47.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P15313
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP6V1B1, Endomembrane proton pump 58 kDa subunit, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1, VPP3, V-type proton ATPase subunit B, kidney isoform, VATB, ATP6B1
Impairment of endocytosis-related factors FNBP1L, ARHGAP24, and ATP6V1B1 increases HIV-1 entry into dendritic cells., PMID:40029073
[Research progress on inherited distal renal tubular acidosis due to variants of V-ATPase-related genes]., PMID:39528293
Clinical Features and Unusual Heterozygous Mutations in Patients with Renal Hypokalemia., PMID:39382926
Identifying key pathogenic mechanisms and potential intervention targets for recurrence after laryngeal cancer treatment through bioinformatics screening., PMID:39145096
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway., PMID:38735913
Medullary Sponge Kidney and Its Relationship with Primary Distal Renal Tubular Acidosis: Case Reports and a Comprehensive Genetics-First Approach., PMID:38447554
Genotype-Phenotype correlation of distal renal tubular acidosis in Tunisia., PMID:38445406
Urinary Acidification Does Not Explain the Absence of Nephrocalcinosis in a Mouse Model of Familial Hypomagnesaemia with Hypercalciuria and Nephrocalcinosis (FHHNC)., PMID:38339056
A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish., PMID:38277730
The B1 H + -ATPase ( Atp6v1b1 ) Subunit in Non-Type A Intercalated Cells is Required for Driving Pendrin Activity and the Renal Defense Against Alkalosis., PMID:37990364
Generation of Atp6v1g3-Cre mice for investigation of intercalated cells and the collecting duct., PMID:37823193
Neonatal Onset Distal Renal Tubular Acidosis: Description of Two Novel Variants on the ATP6V0A4 Gene and Review of the Literature on Associated Extrarenal Manifestations., PMID:39502851
Distal renal tubular acidosis as presenting manifestation of Wilson disease in a 11-year-old girl., PMID:37415038
Hearing Loss Related to Gene Mutations in Distal Renal Tubular Acidosis., PMID:37121229
The pathophysiology of distal renal tubular acidosis., PMID:37016093
High ATP6V1B1 expression is associated with poor prognosis and platinum‑based chemotherapy resistance in epithelial ovarian cancer., PMID:36999629
Transcriptomic profile comparison reveals conservation of ionocytes across multiple organs., PMID:36864051
The transcription factor Foxi1 promotes expression of V-ATPase and Gpr116 in M-1 cells., PMID:36603001
Single-Cell Gene Expression Analysis in Patients with Medullary Sponge Kidney and a Retrospective Study., PMID:36408280
[Epidemiological, clinical and evolutionary particularities of primary distal tubular acidosis in Tunisian children]., PMID:36216732
A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish., PMID:36130215
Evidence for the involvement of branchial Vacuolar-type H+-ATPase in the acidification of the external medium by the West African lungfish, Protopterus annectens, exposed to ammonia-loading conditions., PMID:35987338
[Genotype-phenotype analysis and prognosis in children with primary distal renal tubular acidosis]., PMID:35768359
Genetic and clinical profile of patients with hypophosphatemic rickets., PMID:35738466
Exploration of Different Hypoxia Patterns and Construction of a Hypoxia-Related Gene Prognostic Index in Colorectal Cancer., PMID:35711425
Genetic testing enables a precision medicine approach for nephrolithiasis and nephrocalcinosis in pediatrics: a single-center cohort., PMID:35612621
Genetic heterogeneity in GJB2, COL4A3, ATP6V1B1 and EDNRB variants detected among hearing impaired families in Morocco., PMID:35301649
Potential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Corona Virus 2 Infection/COVID 19 Through RNA Sequencing and Bioinformatics Analysis., PMID:34992355
Hearing loss in Africa: current genetic profile., PMID:34609590
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease., PMID:34313551
Hereditary distal renal tubular acidosis: Genotypic correlation, evolution to long term, and new therapeutic perspectives., PMID:36165107
Genotypic and phenotypic analysis in 51 Chinese patients with primary distal renal tubular acidosis., PMID:34159584
Identification of seven exonic variants in the SLC4A1, ATP6V1B1, and ATP6V0A4 genes that alter RNA splicing by minigene assay., PMID:34157794
Molecular aspects and long-term outcome of patients with primary distal renal tubular acidosis., PMID:33881640
Cancer stem cell transcriptome landscape reveals biomarkers driving breast carcinoma heterogeneity., PMID:33389402
Rab11B participates in erythrocyte storage lesion of under-collected whole blood., PMID:33341364
Phenotypic variability in distal acidification defects associated with WDR72 mutations., PMID:33033857
Downregulated ATP6V1B1 expression acidifies the intracellular environment of cancer cells leading to resistance to antibody-dependent cellular cytotoxicity., PMID:33000417
Evaluation of phenotypic and genotypic features of children with distal kidney tubular acidosis., PMID:32613277
Screening and function discussion of a hereditary renal tubular acidosis family pathogenic gene., PMID:32123165
Molecular Diagnosis and Identification of Genetic Variants Underlying Distal Renal Tubular Acidosis in Pakistani Patients Using Whole Exome Sequencing., PMID:31999492
Whole exome sequencing identified ATP6V1C2 as a novel candidate gene for recessive distal renal tubular acidosis., PMID:31959358
A rare case of autosomal recessive ATP6V0A4 variant of distal renal tubular acidosis in a young female with recurrent nephrolithiasis., PMID:31929293
ATP6V1B1 recurrent mutations in Algerian deaf patients associated with renal tubular acidosis., PMID:31733597
Novel IQCE variations confirm its role in postaxial polydactyly and cause ciliary defect phenotype in zebrafish., PMID:31549751
Sex-dependent differences in water homeostasis in wild-type and V-ATPase B1-subunit deficient mice., PMID:31386675
Distal renal tubular acidosis: genetic causes and management., PMID:31079338
Renal Tubular Acidosis Presenting as Nephrogenic Diabetes Insipidus., PMID:31064905
Presence of serum autoantibodies to vacuolar H+ -ATPase in patients with renal tubular acidosis., PMID:30821427
For research use only. Not for human or drug use.
