Catalog No.
YHA37301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr357-Leu600
Predicted molecular weight
29.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14983
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP2A1, Calcium pump 1, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, SERCA1, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, SR Ca(2+)-ATPase 1
A case with a novel GATA1 variant mimicking immune thrombocytopenia attacks., PMID:40323132
ATP2A2 regulates STING1/MITA-driven signal transduction including selective autophagy., PMID:40265346
Effects of acteoside from Cistanche tubulosa on the plasma metabolome of cancer-related fatigue mice inoculated with colon cancer cells., PMID:39872045
The juxtamembrane sequence of small ankyrin 1 mediates the binding of its cytoplasmic domain to SERCA1 and is required for inhibitory activity., PMID:39863105
Effects of 8 Weeks of Moderate- or High-Volume Strength Training on Sarcoplasmic Reticulum Ca2+ Handling in Elite Female and Male Rowers., PMID:39831408
The Accordion Zebrafish tq206 Mutant in the Assessment of a Novel Pharmaceutical Approach to Brody Myopathy., PMID:39273176
Targeting ATP2B1 impairs PI3K/Akt/FOXO signaling and reduces SARS-COV-2 infection and replication., PMID:38816514
Dendrobium officinale regulate lipid metabolism in diabetic mouse liver via PPAR-RXR signaling pathway: Evidence from an integrated multi-omics analysis., PMID:38460364
The Effects of Aging on Sarcoplasmic Reticulum-Related Factors in the Skeletal Muscle of Mice., PMID:38396828
Case report: Revealing the rare-a Brody Disease patient from Turkey expanding the phenotype., PMID:38125752
Vascular dysfunction caused by loss of Brn-3b/POU4F2 transcription factor in aortic vascular smooth muscle cells is linked to deregulation of calcium signalling pathways., PMID:38007517
Integrative Proteogenomics for Differential Expression and Splicing Variation in a DM1 Mouse Model., PMID:37993104
Identification of potential drug targets for rheumatoid arthritis from genetic insights: a Mendelian randomization study., PMID:37697373
Identification and validation of a cellular senescence-related lncRNA signature for prognostic prediction in patients with multiple myeloma., PMID:37227248
Associative analysis of multi-omics data indicates that acetylation modification is widely involved in cigarette smoke-induced chronic obstructive pulmonary disease., PMID:36714109
Integrating Network Pharmacology and Transcriptomic Strategies to Explore the Pharmacological Mechanism of Hydroxysafflor Yellow A in Delaying Liver Aging., PMID:36430769
Sustainable recovery of MBNL activity in autoregulatory feedback loop in myotonic dystrophy., PMID:36420218
Differential Analysis of Gly211Val and Gly286Val Mutations Affecting Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA1) in Congenital Pseudomyotonia Romagnola Cattle., PMID:36293223
The Notch signaling pathway in skeletal muscle health and disease., PMID:35968817
Identification of Potential Biomarkers for Ryanodine Receptor 1 (RYR1) Mutation-Associated Myopathies Using Bioinformatics Approach., PMID:35692882
Four calcium signaling pathway-related genes were upregulated in microcystic adnexal carcinoma: transcriptome analysis and immunohistochemical validation., PMID:35509066
Quantification of the calcium signaling deficit in muscles devoid of triadin., PMID:35213584
Sarcoplasmic reticulum Ca2+ ATPases genes differential expression in breast cancer cells., PMID:35133336
Transcriptomic-Based Identification of the Immuno-Oncogenic Signature of Cholangiocarcinoma for HLC-018 Multi-Target Therapy Exploration., PMID:34831096
Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight., PMID:34769190
Transcriptome aberration associated with altered locomotor behavior of zebrafish (Danio rerio) caused by Waterborne Benzo[a]pyrene., PMID:34710819
Altered SERCA Expression in Breast Cancer., PMID:34684111
High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1)., PMID:34520479
Maximal strength training-induced increase in efferent neural drive is not reflected in relative protein expression of SERCA., PMID:34498135
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci., PMID:34489471
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing., PMID:34158615
Effects of bisphenol A exposure during cardiac cell differentiation., PMID:34126515
Transcriptome profiling analysis of muscle tissue reveals potential candidate genes affecting water holding capacity in Chinese Simmental beef cattle., PMID:34099805
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanism., PMID:33853474
Persistent mdx diaphragm alterations are accompanied by increased expression and activity of calcium and muscle-specific proteins., PMID:33825181
Gain-of-Function STIM1 L96V Mutation Causes Myogenesis Alteration in Muscle Cells From a Patient Affected by Tubular Aggregate Myopathy., PMID:33718371
Next-generation sequencing application to investigate skeletal muscle channelopathies in a large cohort of Italian patients., PMID:33573884
Post-weaning protein malnutrition induces myocardial dysfunction associated with oxidative stress and altered calcium handling proteins in adult rats., PMID:33555533
Sarcolipin Exhibits Abundant RNA Transcription and Minimal Protein Expression in Horse Gluteal Muscle., PMID:33202832
Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity., PMID:33159855
Famoxadone-cymoxanil induced cardiotoxicity in zebrafish embryos., PMID:32961491
Improvement of eggshell quality by dietary N-carbamylglutamate supplementation in laying chickens., PMID:32731996
The Dimeric Form of 1,3-Diaminoisoquinoline Derivative Rescued the Mis-splicing of Atp2a1 and Clcn1 Genes in Myotonic Dystrophy Type 1 Mouse Model., PMID:32449537
Identification of novel methylation markers in HPV-associated oropharyngeal cancer: genome-wide discovery, tissue verification and validation testing in ctDNA., PMID:32415241
Clinical, morphological and genetic characterization of Brody disease: an international study of 40 patients., PMID:32040565
Structural Changes of Sarco/Endoplasmic Reticulum Ca2+-ATPase Induced by Rutin Arachidonate: A Molecular Dynamics Study., PMID:32024167
Brody myopathy demonstrates a pseudo-increment on repetitive nerve stimulation., PMID:31944327
Graphene oxide quantum dot exposure induces abnormalities in locomotor activities and mechanisms in zebrafish (Danio rerio)., PMID:31943283
Perlecan/Hspg2 deficiency impairs bone's calcium signaling and associated transcriptome in response to mechanical loading., PMID:31715337
NF-YA overexpression protects from glutamine deprivation., PMID:31706909
For research use only. Not for human or drug use.
