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Recombinant Human ARFGAP1 Protein, N-His

Catalog #:   YHK65701 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q8N6T3
Protein length: Met1-Gly121
Overview

Catalog No.

YHK65701

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Gly121

Predicted molecular weight

16.07 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q8N6T3

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

ARF1 GAP, ARF1GAP, ADP-ribosylation factor GTPase-activating protein 1, ARFGAP1, ADP-ribosylation factor 1 GTPase-activating protein, ARF GAP 1, ARF1-directed GTPase-activating protein

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human ARFGAP1 Protein
References

ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis., PMID:40196537

C9orf72 Toxic Species Affect ArfGAP-1 Function., PMID:37566088

Bioinformatic Analysis of Genetic Factors from Human Blood Samples and Postmortem Brains in Parkinson's Disease., PMID:36593912

GARP dysfunction results in COPI displacement, depletion of Golgi v-SNAREs and calcium homeostasis proteins., PMID:36578782

Detection of mosaic variants using genome sequencing in a large pediatric cohort., PMID:36563179

ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier., PMID:34493279

Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells., PMID:34096300

Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1., PMID:34040545

ArfGAP1 inhibits mTORC1 lysosomal localization and activation., PMID:33988249

ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells., PMID:33721634

ArfGAP1 acts as a GTPase-activating protein for human ADP-ribosylation factor-like 1 protein., PMID:33715220

The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats., PMID:33436318

BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection., PMID:33277377

The Proteome and Secretome of Cortical Brain Cells Infected With Herpes Simplex Virus., PMID:32973653

Differential Expression and miRNA-Gene Interactions in Early and Late Mild Cognitive Impairment., PMID:32872134

The roles of the diversity of amphipathic lipids in shaping membranes by membrane-shaping proteins., PMID:32597479

Detection of the in vitro modulation of Plasmodium falciparum Arf1 by Sec7 and ArfGAP domains using a colorimetric plate-based assay., PMID:32144363

Candidate Genes Associated with Delayed Neuropsychomotor Development and Seizures in a Patient with Ring Chromosome 20., PMID:32082653

Methionine Adenosyltransferase 2β Participates in Mouse Oocyte Maturation by Regulating the MAPK Pathway., PMID:32046373

Revealing the mechanism of protein-lipid interactions for a putative membrane curvature sensor in plant endoplasmic reticulum., PMID:31874147

Dissection of GTPase-activating proteins reveals functional asymmetry in the COPI coat of budding yeast., PMID:31331965

Elucidating the Host Interactome of EV-A71 2C Reveals Viral Dependency Factors., PMID:31001221

Effect of Membrane Lipid Packing on Stable Binding of the ALPS Peptide., PMID:30633866

SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis., PMID:30559289

Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements., PMID:30483236

Detecting phospholipase activity with the amphipathic lipid packing sensor motif of ArfGAP1., PMID:30249399

GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis., PMID:30209366

Membrane Curvature Sensing by Amphipathic Helices: Insights from Implicit Membrane Modeling., PMID:29742406

Expression profiling analysis of autophagy-related genes in perineural invasion of cutaneous squamous cell carcinoma., PMID:29552123

High abundance of ArfGAP1 found in the mossy fibers in hilus of the dentate gyrus region of the mouse brain., PMID:29240824

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton., PMID:29141986

Dash-and-Recruit Mechanism Drives Membrane Curvature Recognition by the Small Bacterial Protein SpoVM., PMID:29102609

Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1)., PMID:27531749

Structural characterization of coatomer in its cytosolic state., PMID:27472951

AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway., PMID:27411398

Structural basis for the binding of tryptophan-based motifs by δ-COP., PMID:26578768

Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster., PMID:26565960

Structure-activity relationship studies of QS11, a small molecule Wnt synergistic agonist., PMID:26152429

Structural basis for the geometry-driven localization of a small protein., PMID:25825747

Proteomic profiling reveals autoimmune targets in sarcoidosis., PMID:25608002

ARFGAP1 is dynamically associated with lipid droplets in hepatocytes., PMID:25397679

Phospholipase D2 is involved in the formation of Golgi tubules and ArfGAP1 recruitment., PMID:25354038

A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment., PMID:25222832

Gene expression profiles on predicting protein interaction network and exploring of new treatments for lung cancer., PMID:25205123

Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex., PMID:25139911

Interaction of LRRK2 with kinase and GTPase signaling cascades., PMID:25071441

Sensing membrane stresses by protein insertions., PMID:24722359

Hepatitis C virus NS5A hijacks ARFGAP1 to maintain a phosphatidylinositol 4-phosphate-enriched microenvironment., PMID:24623438

ArfGAP3 regulates the transport of cation-independent mannose 6-phosphate receptor in the post-Golgi compartment., PMID:24076238

Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs., PMID:24048449

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human ARFGAP1 Protein, N-His [YHK65701]
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