Catalog No.
YHK65701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly121
Predicted molecular weight
16.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8N6T3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ARF1 GAP, ARF1GAP, ADP-ribosylation factor GTPase-activating protein 1, ARFGAP1, ADP-ribosylation factor 1 GTPase-activating protein, ARF GAP 1, ARF1-directed GTPase-activating protein
ATG2A engages Rab1a and ARFGAP1 positive membranes during autophagosome biogenesis., PMID:40196537
C9orf72 Toxic Species Affect ArfGAP-1 Function., PMID:37566088
Bioinformatic Analysis of Genetic Factors from Human Blood Samples and Postmortem Brains in Parkinson's Disease., PMID:36593912
GARP dysfunction results in COPI displacement, depletion of Golgi v-SNAREs and calcium homeostasis proteins., PMID:36578782
Detection of mosaic variants using genome sequencing in a large pediatric cohort., PMID:36563179
ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier., PMID:34493279
Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells., PMID:34096300
Constitutive Endocytosis of the Neuronal Glutamate Transporter Excitatory Amino Acid Transporter-3 Requires ARFGAP1., PMID:34040545
ArfGAP1 inhibits mTORC1 lysosomal localization and activation., PMID:33988249
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells., PMID:33721634
ArfGAP1 acts as a GTPase-activating protein for human ADP-ribosylation factor-like 1 protein., PMID:33715220
The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats., PMID:33436318
BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection., PMID:33277377
The Proteome and Secretome of Cortical Brain Cells Infected With Herpes Simplex Virus., PMID:32973653
Differential Expression and miRNA-Gene Interactions in Early and Late Mild Cognitive Impairment., PMID:32872134
The roles of the diversity of amphipathic lipids in shaping membranes by membrane-shaping proteins., PMID:32597479
Detection of the in vitro modulation of Plasmodium falciparum Arf1 by Sec7 and ArfGAP domains using a colorimetric plate-based assay., PMID:32144363
Candidate Genes Associated with Delayed Neuropsychomotor Development and Seizures in a Patient with Ring Chromosome 20., PMID:32082653
Methionine Adenosyltransferase 2β Participates in Mouse Oocyte Maturation by Regulating the MAPK Pathway., PMID:32046373
Revealing the mechanism of protein-lipid interactions for a putative membrane curvature sensor in plant endoplasmic reticulum., PMID:31874147
Dissection of GTPase-activating proteins reveals functional asymmetry in the COPI coat of budding yeast., PMID:31331965
Elucidating the Host Interactome of EV-A71 2C Reveals Viral Dependency Factors., PMID:31001221
Effect of Membrane Lipid Packing on Stable Binding of the ALPS Peptide., PMID:30633866
SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis., PMID:30559289
Chaperones, Membrane Trafficking and Signal Transduction Proteins Regulate Zaire Ebola Virus trVLPs and Interact With trVLP Elements., PMID:30483236
Detecting phospholipase activity with the amphipathic lipid packing sensor motif of ArfGAP1., PMID:30249399
GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis., PMID:30209366
Membrane Curvature Sensing by Amphipathic Helices: Insights from Implicit Membrane Modeling., PMID:29742406
Expression profiling analysis of autophagy-related genes in perineural invasion of cutaneous squamous cell carcinoma., PMID:29552123
High abundance of ArfGAP1 found in the mossy fibers in hilus of the dentate gyrus region of the mouse brain., PMID:29240824
ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton., PMID:29141986
Dash-and-Recruit Mechanism Drives Membrane Curvature Recognition by the Small Bacterial Protein SpoVM., PMID:29102609
Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1)., PMID:27531749
Structural characterization of coatomer in its cytosolic state., PMID:27472951
AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway., PMID:27411398
Structural basis for the binding of tryptophan-based motifs by δ-COP., PMID:26578768
Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster., PMID:26565960
Structure-activity relationship studies of QS11, a small molecule Wnt synergistic agonist., PMID:26152429
Structural basis for the geometry-driven localization of a small protein., PMID:25825747
Proteomic profiling reveals autoimmune targets in sarcoidosis., PMID:25608002
ARFGAP1 is dynamically associated with lipid droplets in hepatocytes., PMID:25397679
Phospholipase D2 is involved in the formation of Golgi tubules and ArfGAP1 recruitment., PMID:25354038
A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment., PMID:25222832
Gene expression profiles on predicting protein interaction network and exploring of new treatments for lung cancer., PMID:25205123
Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex., PMID:25139911
Interaction of LRRK2 with kinase and GTPase signaling cascades., PMID:25071441
Sensing membrane stresses by protein insertions., PMID:24722359
Hepatitis C virus NS5A hijacks ARFGAP1 to maintain a phosphatidylinositol 4-phosphate-enriched microenvironment., PMID:24623438
ArfGAP3 regulates the transport of cation-independent mannose 6-phosphate receptor in the post-Golgi compartment., PMID:24076238
Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs., PMID:24048449