Catalog No.
YHK65101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu16-Lys378
Predicted molecular weight
43.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8IUR7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ARMC8, Armadillo repeat-containing protein 8
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway., PMID:40346622
The interactome of tau phosphorylated at T217 in Alzheimer's disease human brain tissue., PMID:40317322
GID complex regulates the differentiation of neural stem cells by destabilizing TET2., PMID:37707676
MiR-455-3p inhibits gastric cancer progression by repressing Wnt/β-catenin signaling through binding to ARMC8., PMID:37400847
Discovery of differentially expressed novel miRNAs in breast normal cells and their putative targets., PMID:36680668
The expression and prognostic significance of PIK3CB in lung adenocarcinoma., PMID:35780638
Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas., PMID:34016486
MiR-664 Protects Against UVB Radiation-Induced HaCaT Cell Damage via Downregulating ARMC8., PMID:32547335
The CTLH Complex in Cancer Cell Plasticity., PMID:31885576
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan., PMID:31795790
The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation., PMID:31285494
The micro RNA hsa-miR-377-3p inhibits tumor growth in malignant melanoma., PMID:35516861
Armc8 is an evolutionarily conserved armadillo protein involved in cell-cell adhesion complexes through multiple molecular interactions., PMID:30482882
Molecular cloning, characterization and expression analysis of ARMC6, ARMC7, ARMC8 from Pacific white shrimp, Litopenaeus vannamei., PMID:30292870
Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses., PMID:30036398
Silencing of Armadillo Repeat-Containing Protein 8 (ARMc8) Inhibits TGF-β-Induced EMT in Bladder Carcinoma UMUC3 Cells., PMID:28081738
Armadillo Repeat-Containing Protein 8 (ARMC8) Silencing Inhibits Proliferation and Invasion in Osteosarcoma Cells., PMID:27712595
ARMc8: a potential diagnostic and therapeutic target for cancers-reply., PMID:27036315
ARMc8: a potential diagnostic and therapeutic target for cancers., PMID:27036312
Armc8 regulates the invasive ability of hepatocellular carcinoma through E-cadherin/catenin complex., PMID:26944057
A novel biomarker ARMc8 promotes the malignant progression of ovarian cancer., PMID:26232863
ARMc8 indicates aggressive colon cancers and promotes invasiveness and migration of colon cancer cells., PMID:26081621
Comparative proteomics and global genome-wide expression data implicate role of ARMC8 in lung cancer., PMID:25987023
The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels., PMID:25329471
Armc8 expression was elevated during atypia-to-carcinoma progression and associated with cancer development of breast carcinoma., PMID:25119601
ARMC8α promotes proliferation and invasion of non-small cell lung cancer cells by activating the canonical Wnt signaling pathway., PMID:24894675
Molecular phylogeny of a RING E3 ubiquitin ligase, conserved in eukaryotic cells and dominated by homologous components, the muskelin/RanBPM/CTLH complex., PMID:24143168
Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin., PMID:23997114
Armadillo Repeat Containing 8alpha Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins., PMID:20224683
Proteasome-dependent degradation of alpha-catenin is regulated by interaction with ARMc8alpha., PMID:18215130
RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex., PMID:17467196
For research use only. Not for human or drug use.
