Catalog No.
YHG48801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met68-Leu291
Predicted molecular weight
26.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13326
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Gamma-sarcoglycan, SGCG, 35 kDa dystrophin-associated glycoprotein, 35DAG, Gamma-SG
Inherited and de novo variants in young females potentially associated with pelvic organ prolapse., PMID:40157519
Sarcoglycanopathies: From clinical diagnosis to new promising therapies., PMID:40129306
Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis., PMID:39909125
The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome., PMID:39790063
Profiling of pathogenic variants in Japanese patients with sarcoglycanopathy., PMID:39755676
Phenotypic Variability of LGMD 2C/R5 in a Genetically Homogenous Group of Bulgarian Muslim Roma., PMID:39336735
Genetic spectrum of sarcoglycanopathies in a cohort of Russian patients., PMID:38876406
Defining clinical endpoints in limb girdle muscular dystrophy: a GRASP-LGMD study., PMID:38491364
Single-centre experience with autosomal recessive limb-girdle muscular dystrophy: case series and literature review., PMID:37852290
Combined sequence and copy number analysis improves diagnosis of limb girdle and other myopathies., PMID:37688281
Targeted next-generation sequencing determined a novel SGCG variant that is associated with limb-girdle muscular dystrophy type 2C: A case report., PMID:36992678
Systemic γ-sarcoglycan AAV gene transfer results in dose-dependent correction of muscle deficits in the LGMD 2C/R5 mouse model., PMID:36816759
Homozygous Inversion on Chromosome 13 Involving SGCG Detected by Short Read Whole Genome Sequencing in a Patient Suffering from Limb-Girdle Muscular Dystrophy., PMID:36292638
Comparative genomic analyses of multiple backcross mouse populations suggest SGCG as a novel potential obesity-modifier gene., PMID:35796564
Clinical, genetic profile and disease progression of sarcoglycanopathies in a large cohort from India: high prevalence of SGCB c.544A > C., PMID:35416532
Novel γ-sarcoglycan interactors in murine muscle membranes., PMID:35065666
The utility of whole-exome sequencing in accurate diagnosis of neuromuscular disorders in consanguineous families in Jordan., PMID:34624274
Clinical and genetic spectrum of a large cohort of patients with δ-sarcoglycan muscular dystrophy., PMID:34515763
Sarcoglycanopathies: an update., PMID:34404573
Elucidation of the Genetic Cause in Dutch Limb Girdle Muscular Dystrophy Families: A 27-Year's Journey., PMID:33386810
The etiology of rhabdomyolysis: an interaction between genetic susceptibility and external triggers., PMID:32978841
New genotype-phenotype correlations in a large European cohort of patients with sarcoglycanopathy., PMID:32875335
SGCG rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program., PMID:32527767
Expression, purification, and structural analysis of the full-length human integral membrane protein γ-sarcoglycan., PMID:31682967
Association of a novel seven-gene expression signature with the disease prognosis in colon cancer patients., PMID:31612869
A gene-edited mouse model of limb-girdle muscular dystrophy 2C for testing exon skipping., PMID:31582396
Childhood onset limb-girdle muscular dystrophies in the Aegean part of Turkey., PMID:30838351
Molecular genetic study of Calpainopathy in Iran., PMID:30056071
A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease., PMID:29986096
Efficient exon skipping of SGCG mutations mediated by phosphorodiamidate morpholino oligomers., PMID:29720576
Contrast-Enhanced Near-Infrared Optical Imaging Detects Exacerbation and Amelioration of Murine Muscular Dystrophy., PMID:29271299
Severe murine limb-girdle muscular dystrophy type 2C pathology is diminished by FTY720 treatment., PMID:27935071
γ-sarcoglycan and dystrophin mutation spectrum in an Algerian cohort., PMID:27759885
Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus., PMID:27560143
A rare form of limb girdle muscular dystrophy (type 2E) seen in an Iranian family detected by autozygosity mapping., PMID:27276190
Analysis of lncRNAs expression in UVB-induced stress responses of melanocytes., PMID:26596215
Biochemical and Functional Comparisons of mdx and Sgcg(-/-) Muscular Dystrophy Mouse Models., PMID:26064876
The Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels., PMID:25698924
Excess SMAD signaling contributes to heart and muscle dysfunction in muscular dystrophy., PMID:25070948
Sarcolemmal alpha and gamma sarcoglycan protein deficiencies in Turkish siblings with a novel missense mutation in the alpha sarcoglycan gene., PMID:24742800
Carrier frequency of the c.525delT mutation in the SGCG gene and estimated prevalence of limb girdle muscular dystrophy type 2C among the Moroccan population., PMID:24552312
Puerto Rican founder mutation G787A in the SGCG gene: a case report of 2 siblings with LGMD 2C., PMID:24534832
Identification of HMX1 target genes: a predictive promoter model approach., PMID:23946633
Hints of unique genetic effects for type 2 diabetes in India., PMID:23613552
Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India., PMID:23300278
The superhealing MRL background improves muscular dystrophy., PMID:23216833
Acute ischemic stroke in gamma-sarcoglycanopathy., PMID:23040950
Impact of single-nucleotide polymorphisms at the TP53-binding and responsive promoter region of BCL2 gene in modulating the phenotypic variability of LGMD2C patients., PMID:22367371
Motor chip: a comparative genomic hybridization microarray for copy-number mutations in 245 neuromuscular disorders., PMID:21896784
For research use only. Not for human or drug use.
