Catalog No.
YHE45501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr58-Tyr432
Predicted molecular weight
43.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P45954
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
2-methyl branched chain acyl-CoA dehydrogenase, SBCAD, 2-MEBCAD, 2-methylbutyryl-CoA dehydrogenase, ACADSB, Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, 2-methylbutyryl-coenzyme A dehydrogenase
The interaction of HT-2 toxin and Akt1 on gene expression regulation in Kashin-Beck disease pathogenesis., PMID:40449756
Integrated Amino Acid Profiling and 4D-DIA Proteomics Reveal Protein Quality Divergence and Metabolic Adaptation in Cordyceps Species., PMID:40422699
Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis., PMID:40148878
Convergent relaxation of molecular constraint in herbivores reveals the changing role of liver and kidney functions across mammalian diets., PMID:39578099
Integrative analysis of non12-hydroxylated bile acid revealed the suppressed molecular map of alternative pathway in nonalcoholic steatohepatitis mice., PMID:39556333
Bioinformatics and system biology approaches to determine the connection of SARS-CoV-2 infection and intrahepatic cholangiocarcinoma., PMID:38648205
Identification of important modules and biomarkers in diabetic cardiomyopathy based on WGCNA and LASSO analysis., PMID:38469146
Pathogenic/likely pathogenic mutations identified in Vietnamese children diagnosed with autism spectrum disorder using high-resolution SNP genotyping platform., PMID:38287090
The impact of dietary Laminaria digitata and alginate lyase supplementation on the weaned piglet liver: A comprehensive proteomics and metabolomics approach., PMID:38151157
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation., PMID:38081477
A Newly Established Cuproptosis-Related Gene Signature for Predicting Prognosis and Immune Infiltration in Uveal Melanoma., PMID:37511120
Acyl-CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism., PMID:37309295
A multicenter prospective study of next-generation sequencing-based newborn screening for monogenic genetic diseases in China., PMID:36847978
miR-23b-3p regulates human endometrial epithelial cell adhesion implying a role in implantation., PMID:36757298
[Analysis of clinical features, biochemical indices and genetic variants among children with Short/branched-chain acyl-CoA dehydrogenase deficiency detected by neonatal screening]., PMID:36709932
Comprehensive analysis of immune ferroptosis gene in renal clear cell carcinoma: prognosis and influence of tumor microenvironment., PMID:36247256
Long-term monitoring for short/branched-chain acyl-CoA dehydrogenase deficiency: A single-center 4-year experience and open issues., PMID:36147814
ITCH E3 ubiquitin ligase downregulation compromises hepatic degradation of branched-chain amino acids., PMID:35150905
Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA., PMID:34943861
ACADSB regulates ferroptosis and affects the migration, invasion, and proliferation of colorectal cancer cells., PMID:32776663
Regulation of Actg1 and Gsta2 is possible mechanism by which capsaicin alleviates apoptosis in cell model of 6-OHDA-induced Parkinson's disease., PMID:32537633
Weaning Alters Intestinal Gene Expression Involved in Nutrient Metabolism by Shaping Gut Microbiota in Pigs., PMID:32362884
An association analysis for 14 candidate genes mapping to meat quality quantitative trait loci in a Duroc pig population reveals that the ATP1A2 genotype is highly associated with muscle electric conductivity., PMID:31633210
Genome-Wide Association Study for Milk Protein Composition Traits in a Chinese Holstein Population Using a Single-Step Approach., PMID:30838020
Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours., PMID:30176945
Proteomic analysis reveals the distinct energy and protein metabolism characteristics involved in myofiber type conversion and resistance of atrophy in the extensor digitorum longus muscle of hibernating Daurian ground squirrels., PMID:29482114
Influence of Delipation on the Energy Metabolism in Pig Parthenogenetically Activated Embryos., PMID:26303295
Genotype-based databases for variants causing rare diseases., PMID:25111118
Prevalence and mutation analysis of short/branched chain acyl-CoA dehydrogenase deficiency (SBCADD) detected on newborn screening in Wisconsin., PMID:23712021
Common genetic variants in the vitamin D pathway including genome-wide associated variants are not associated with breast cancer risk among Chinese women., PMID:21828234
Characterization of new ACADSB gene sequence mutations and clinical implications in patients with 2-methylbutyrylglycinuria identified by newborn screening., PMID:20547083
Genome-wide association study of circulating vitamin D levels., PMID:20418485
2-Methylbutyryl-coenzyme A dehydrogenase deficiency: functional and molecular studies on a defect in isoleucine catabolism., PMID:17945527
Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsy specimens, using a large-scale real-time reverse transcription-PCR approach., PMID:17158757
Association of genetic polymorphisms of ACADSB and COMT with human hypertension., PMID:17143180
Inborn errors of isoleucine degradation: a review., PMID:16950638
2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation., PMID:15615815
Localization of short/branched chain acyl-CoA dehydrogenase (ACADSB) to human chromosome 10., PMID:7759115
Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family., PMID:7698750
For research use only. Not for human or drug use.
