Catalog No.
YHG12201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg121-Arg195
Predicted molecular weight
21.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q07352
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ERF-1, ZFP36-like 1, TIS11B, BRF1, ZFP36L1, Butyrate response factor 1, Zinc finger protein 36, C3H1 type-like 1, ERF1, RNF162B, BERG36, TPA-induced sequence 11b, mRNA decay activator protein ZFP36L1, EGF-response factor 1
ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis., PMID:40328742
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness., PMID:40249077
The zinc finger protein ZFP36L2 inhibits flavivirus infection via the 5'-3' XRN1-mediated RNA decay pathway in the replication complexes., PMID:39972499
Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC., PMID:39894886
Cytoplasmic mRNA decay controlling inflammatory gene expression is determined by pre-mRNA fate decision., PMID:39862867
Identification and validation of a novel defined stress granule-related gene signature for predicting the prognosis of ovarian cancer via bioinformatics analysis., PMID:39809219
ZFP36 Facilitates Senecavirus A (SVA) replication by inhibiting the production of type I interferon., PMID:39547416
Super-enhancer-driven ZFP36L1 promotes PD-L1 expression in infiltrative gastric cancer., PMID:39373630
ZFP36L1 and ZFP36L2 reduce cyclin D1 expression by decreasing expression of E2F1 and long 3'UTR isoform of CCND1 transcripts., PMID:39110278
ZFP36 family expression is suppressed by Th2 cells in asthma, leading to enhanced synthesis of inflammatory cytokines and cell surface molecules., PMID:39067169
LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1., PMID:38804344
ZFP36L1 controls KLF16 mRNA stability in vascular smooth muscle cells during restenosis after vascular injury., PMID:38653384
Zinc finger protein 36 like 2-histone deacetylase 1 axis is involved in the bone responses to mechanical stress., PMID:38604490
Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis and Bacillus anthracis Lethal Toxin-Induced Thrombocytopenia., PMID:38542074
Lipopolysaccharide regulation of antiinflammatory tristetraprolin family and proinflammatory gene expression in mouse macrophages., PMID:38504371
MicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence., PMID:38317146
Zfp36l1 establishes the high-affinity CD8 T-cell response by directly linking TCR affinity to cytokine sensing., PMID:38039407
Low expression of ZFP36L1 in osteosarcoma promotes lung metastasis by inhibiting the SDC4-TGF-β signaling feedback loop., PMID:37935976
The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma., PMID:37928904
Synergistic roles of tristetraprolin family members in myeloid cells in the control of inflammation., PMID:37903626
Epstein-Barr virus infectious particles initiate B cell transformation and modulate cytokine response., PMID:37830871
Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma., PMID:37801008
Identification of Key Genes Associated with Heat Stress in Rats by Weighted Gene Co-Expression Network Analysis., PMID:37238049
Plant Polyphenol Gossypol Induced Cell Death and Its Association with Gene Expression in Mouse Macrophages., PMID:37189372
[Cloning and expression profile of ZFP36L1 gene in goat]., PMID:37154333
Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function., PMID:37074914
Simplified algorithm for genetic subtyping in diffuse large B-cell lymphoma., PMID:37032379
Predicting Key Genes and Therapeutic Molecular Modelling to Explain the Association between Porphyromonas gingivalis (P. gingivalis) and Alzheimer's Disease (AD)., PMID:36982508
A miR-124-mediated post-transcriptional mechanism controlling the cell fate switch of astrocytes to induced neurons., PMID:36963393
ZFP36 ring finger protein like 1 significantly suppresses human coronavirus OC43 replication., PMID:36846448
A pilot study on identifying gene signatures as markers for predicting patient response to antiseizure medications., PMID:36658410
Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell., PMID:36385275
The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses., PMID:36269839
Single-cell RNA sequencing analysis dissected the osteo-immunology microenvironment and revealed key regulators in osteoporosis., PMID:36257255
Silencing of RNA binding protein, ZFP36L1, promotes epithelial-mesenchymal transition in liver cancer cells by regulating transcription factor ZEB2., PMID:36100056
Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1., PMID:36008402
[ZFP36L1 inhibits proliferation, invasion and migration of human breast cancer cells by inducing epithelial-mesenchymal transition through STAT3/p-STAT3 signaling pathway]., PMID:35851086
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways., PMID:35611776
CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner., PMID:35510877
The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins., PMID:35477960
Conflicting Roles of ZFP36L1 in Regulating the Progression of Muscle Invasive Bladder Cancer., PMID:35359594
SLAMF6 is associated with the susceptibility and severity of rheumatoid arthritis in the Chinese population., PMID:35016729
AU-Rich Element RNA Binding Proteins: At the Crossroads of Post-Transcriptional Regulation and Genome Integrity., PMID:35008519
ZFP36L1 Regulates Fgf21 mRNA Turnover and Modulates Alcoholic Hepatic Steatosis and Inflammation in Mice., PMID:34774847
Functional screen of inflammatory bowel disease genes reveals key epithelial functions., PMID:34758847
Zinc Finger Protein ZFP36L1 Inhibits Flavivirus Infection by both 5'-3' XRN1 and 3'-5' RNA-Exosome RNA Decay Pathways., PMID:34643435
The oncogenic role of HIF-1α/miR-182-5p/ZFP36L1 signaling pathway in nasopharyngeal carcinoma., PMID:34465330
ZFP36 Family Members Regulate the Proinflammatory Features of Psoriatic Dermal Fibroblasts., PMID:34333017
Post-Transcriptional Regulation of Immune Responses and Inflammatory Diseases by RNA-Binding ZFP36 Family Proteins., PMID:34276705
ZFP36L1 plays an ambiguous role in the regulation of cell expansion and negatively regulates CDKN1A in chronic myeloid leukemia cells., PMID:34090970
For research use only. Not for human or drug use.
