Catalog No.
YHK64301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn150
Predicted molecular weight
19.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8TBY8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Polyamine-modulated factor 1-binding protein 1, PMFBP1, PMF-1-binding protein
A homozygous loss-of-function mutation in CEP250 is associated with acephalic spermatozoa syndrome in humans., PMID:39726222
Pathogenesis of acephalic spermatozoa syndrome caused by PMFBP1 mutation., PMID:39668357
Transcriptome and proteome analyses reveal the mechanisms involved in polystyrene nanoplastics disrupt spermatogenesis in mice., PMID:38061432
Identification of Potentially Novel Molecular Targets of Endometrial Cancer Using a Non-Biased Proteomic Approach., PMID:37760635
Loss of PMFBP1 Disturbs Mouse Spermatogenesis by Downregulating HDAC3 Expression., PMID:37423931
Whole-genome sequencing identifies new candidate genes for nonobstructive azoospermia., PMID:36017582
Novel mutations of PMFBP1 in a man with acephalic spermatozoa defects., PMID:35860846
Meta-analysis of sub-Saharan African studies provides insights into genetic architecture of lipid traits., PMID:35546142
BmPMFBP1 regulates the development of eupyrene sperm in the silkworm, Bombyx mori., PMID:35312700
The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus., PMID:34389728
Patients with acephalic spermatozoa syndrome linked to novel TSGA10/PMFBP1 variants have favorable pregnancy outcomes from intracytoplasmic sperm injection., PMID:34089195
A novel homozygous missense mutation of PMFBP1 causes acephalic spermatozoa syndrome., PMID:33484382
Genetic basis of acephalic spermatozoa syndrome, and intracytoplasmic sperm injection outcomes in infertile men: a systematic scoping review., PMID:33452591
Loss-of-function mutation in TSGA10 causes acephalic spermatozoa phenotype in human., PMID:32410354
Novel mutations in PMFBP1, TSGA10 and SUN5: Expanding the spectrum of mutations that may cause acephalic spermatozoa., PMID:32285443
[Advances in the molecular genetic studies of acephalic spermatozoa syndrome]., PMID:32233213
Prevention of multiple system atrophy using human bone marrow-derived mesenchymal stem cells by reducing polyamine and cholesterol-induced neural damages., PMID:32127052
Beyond Acephalic Spermatozoa: The Complexity of Intracytoplasmic Sperm Injection Outcomes., PMID:32104701
Biallelic mutations in PMFBP1 cause acephalic spermatozoa., PMID:30298696
Mutations in PMFBP1 Cause Acephalic Spermatozoa Syndrome., PMID:30032984
Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts., PMID:22170508
Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cells., PMID:11468771
For research use only. Not for human or drug use.
