Catalog No.
YHK64201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met418-Ala518
Predicted molecular weight
22.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92959
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
OATP2A1, Solute carrier family 21 member 2, Prostaglandin transporter, Solute carrier organic anion transporter family member 2A1, SLCO2A1, SLC21A2, PGT
Monogenic SLCO2A1 gene mutation presenting as early onset inflammatory bowel disease-A report of rare case with review of literature., PMID:40405524
Distinct features of three clinical subtypes in 533 patients with primary hypertrophic osteoarthropathy., PMID:40251683
Acetaminophen as a possible treatment option for pachydermoperiostosis carrying mutated SLCO2A1: Case series., PMID:39912343
Chronic enteropathy associated with SLCO2A1 from North India: a rare monogenic condition mimicking Crohn's disease., PMID:39842898
Cigarette smoke-induced attenuation of the prostaglandin transporter SLCO2A1 expression through aryl hydrocarbon receptor., PMID:39608564
A novel mutation in the SLCO2A1 gene presenting as persistent hypoproteinaemia and refractory iron deficiency anaemia due to chronic enteropathy: a case report., PMID:39563252
Single-Cell Meta-Analysis Uncovers the Pancreatic Endothelial Cell Transcriptomic Signature and Reveals a Key Role for NKX2-3 in PLVAP Expression., PMID:39445426
Population Pharmacokinetic and Pharmacodynamic of Atorvastatin in Chinese Lung Transplant Recipients., PMID:39404135
Spatial transcriptomics reveal tumor microenvironment and SLCO2A1 correlated with tumor suppression in hypopharyngeal squamous cell carcinoma., PMID:39340989
Molecular programs guiding arealization of descending cortical pathways., PMID:39261725
Digital clubbing without hypoxia for lysinuric protein intolerance., PMID:39151655
Identification of macrophage differentiation related genes and subtypes linking atherosclerosis plaque processing and metabolic syndrome via integrated bulk and single-cell sequence analysis., PMID:39130409
Discrimination of pediatric cryptogenic multifocal ulcerous stenosing enteritis from small bowel Crohn's disease and gastrointestinal tuberculosis: A retrospective study (with videos)., PMID:38902474
Characteristics of chronic enteropathy associated with SLCO2A1 gene (CEAS) in children, a unique type of monogenic very early-onset inflammatory bowel disease., PMID:38890589
A novel variant in the SLCO2A1 gene in a Chinese patient with chronic gastroenteropathy and primary hypertrophic osteoarthropathy., PMID:38862970
Pathogenesis of chronic enteropathy associated with the SLCO2A1 gene: Hypotheses and conundrums., PMID:38817656
The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population., PMID:38776231
Clinical and genetic characteristics of Chinese patients diagnosed with chronic enteropathy associated with SLCO2A1 gene., PMID:38755710
Lack of cutis verticis gyrata is associated with c.1279_1290del12 of SLCO2A1 in 43 Japanese patients with pachydermoperiostosis., PMID:38644096
Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis., PMID:38415587
Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A10., PMID:38372137
First case report of dichorionic diamniotic twins with chronic enteropathy associated with the SLCO2A1 gene., PMID:38289459
Cranberry Proanthocyanidins Mitigate Reflux-Induced Transporter Dysregulation in an Esophageal Adenocarcinoma Model., PMID:38139823
Genotype and phenotype characterization of primary hypertrophic osteoarthropathy type 2 and chronic enteropathy associated with SLCO2A1: Report of two cases and literature review., PMID:37915296
Evaluation of ADRB2 and OATP2A1 genetic polymorphisms in Indian patients with primary open-angle glaucoma., PMID:37906648
Identification of three novel mutations in SLCO2A1 in Asian-Indians with Pachydermoperiostosis., PMID:37861627
PPARγ regulates lipid metabolism and viability of sheep trophoblast cells., PMID:37712626
Primary hypertrophic osteoarthropathy: genetics, clinical features and management., PMID:37705574
[Three cases of chronic enteropathy associated with SLCO2A1 gene in children]., PMID:37650169
Attenuated Expression of SLCO2A1 Caused by DNA Methylation in Pediatric Inflammatory Bowel Disease., PMID:37327083
Touraine-Solente-Gole syndrome: pathogenic variant in SLCO2A1 presented with polyarthralgia and digital clubbing., PMID:37226222
Eosinophilic enteritis requiring differentiation from chronic enteropathy associated with SLCO2A1 gene: A case report., PMID:37077520
Testing sulforaphane as a strategy against toxic chemicals of public health concern by toxicogenomic data analysis: Friend or foe at the gene level - Colorectal carcinoma case study., PMID:37004859
Expression profile of genes related to pregnancy maintenance in Dromedary Camel during the first trimester., PMID:36990016
A Novel Chronic Enteropathy Associated with SLCO2A1 Gene Mutation: Enterography Findings in a Multicenter Korean Registry., PMID:36907595
Homozygous Missense Variant in the Solute Carrier Organic Anion Transporter 2A1 (SLCO2A1) Gene Underlies Isolated Nail Clubbing., PMID:36833358
Identification and Analysis of Hub Genes and Immune Cells Associated with the Formation of Acute Aortic Dissection., PMID:36818541
Mucosal immune systems of pediatric inflammatory bowel disease: A review., PMID:36799518
N-glycosylation modifies prostaglandin E2 uptake by reducing cell surface expression of SLCO2A1., PMID:36706979
Genetic variations predicting progression with docetaxel and novel androgen-receptor pathway inhibitors., PMID:36602227
Novel pathogenic variants in SLCO2A1 causing autosomal dominant primary hypertrophic osteoarthropathy., PMID:36549465
Crohn-like Disease Affecting Small Bowel Due to Monogenic SLCO2A1 Mutations: First Cases of Chronic Enteropathy Associated with SLCO2A1 Gene [CEAS] in France., PMID:36480694
Chronic enteropathy associated with SLCO2A1 gene and hereditary fructose intolerance: A coincidence of two rare diseases., PMID:36384942
Multiple small intestinal ulcers with SLCO2A1 mutation in a Chinese patient., PMID:36241536
Chronic enteropathy associated with SLCO2A1-associated primary hypertrophic osteoarthropathy in a female patient., PMID:36089247
Pyroptosis, apoptosis, and necroptosis molecular subtype derived prognostic signature universal applicable for gastric cancer-A large sample and multicenter retrospective analysis., PMID:36044785
Functional analysis of mutant SLCO2A1 transporters found in patients with chronic enteropathy associated with SLCO2A1., PMID:35877192
Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations., PMID:35813463
[A case of chronic enteropathy associated with SLCO2A1 gene diagnosed by capsule endoscopy and successfully treated by ferric carboxymaltose]., PMID:35811122
Integrated bioinformatics and statistical approaches to explore molecular biomarkers for breast cancer diagnosis, prognosis and therapies., PMID:35617355