Catalog No.
YHK63601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn29-Gly105
Predicted molecular weight
21.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96HR3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MED30, THRAP6, Mediator complex subunit 30, Thyroid hormone receptor-associated protein 6, TRAP25, TRAP/Mediator complex component TRAP25, Trap25, Mediator of RNA polymerase II transcription subunit 30, Thyroid hormone receptor-associated protein complex 25 kDa component
DNA hypermethylation of MED1 and MED23 as early diagnostic biomarkers for unsolved issues in atrial fibrillation., PMID:40113094
The essential role of MED27 in stabilizing the mediator complex for cardiac development and function., PMID:39209248
Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function., PMID:38661000
Multiple genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β-cell survival and function., PMID:37502937
Immune complexome analysis of a rich variety of serum immune complexes identifies disease-characteristic immune complex antigens in systemic sclerosis., PMID:36436353
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network., PMID:34506481
Structure of the human Mediator-RNA polymerase II pre-initiation complex., PMID:33902108
HIF1α and p53 Regulated MED30, a Mediator Complex Subunit, is Involved in Regulation of Glioblastoma Pathogenesis and Temozolomide Resistance., PMID:32705436
Increasing evidence of pathogenic role of the Mediator (MED) complex in the development of cardiovascular diseases., PMID:31255603
Viral integration drives multifocal HCC during the occult HBV infection., PMID:31200735
The MED30 subunit of mediator complex is essential for early plant development and promotes flowering in Arabidopsis thaliana., PMID:31097434
Cohesin occupancy and composition at enhancers and promoters are linked to DNA replication origin proximity in Drosophila., PMID:30796039
Proteomic Interactome of C. elegans Mediator Complex Subunit 28 (MDT-28) Reveals Predominant Association with a Restricted Set of Core Mediator Subunits and an Affinity to Additional Structural and Enzymatic Proteins., PMID:32362303
Genome-Wide Association Study in Vestibular Neuritis: Involvement of the Host Factor for HSV-1 Replication., PMID:30079052
The knockdown of the mediator complex subunit MED30 suppresses the proliferation and migration of renal cell carcinoma cells., PMID:29661722
Detection of susceptibility loci on APOA5 and COLEC12 associated with metabolic syndrome using a genome-wide association study in a Taiwanese population., PMID:29212154
Genome-wide admixture and association study of subclinical atherosclerosis in the Women's Interagency HIV Study (WIHS)., PMID:29206233
The Contrasting Role of the Mediator Subunit MED30 in the Progression of Bladder Cancer., PMID:29187445
Affection of Comt1 genetype on anxiety and nociceptive sensitivity: an Ego-network analysis approach., PMID:28969474
Prenatal diagnosis and array comparative genomic hybridization characterization of interstitial deletions of 8q23.3-q24.11 and 8q24.13 associated with Langer-Giedion syndrome, Cornelia de Lange syndrome and haploinsufficiency of TRPS1, RAD21 and EXT1., PMID:26522117
MED30 Regulates the Proliferation and Motility of Gastric Cancer Cells., PMID:26110885
Characterization of the influence of mediator complex in HIV-1 transcription., PMID:25100719
The roles of mediator complex in cardiovascular diseases., PMID:24751643
Dissection of open chromatin domain formation by site-specific recombination in Drosophila., PMID:24639466
Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation., PMID:22531626
Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells., PMID:22331469
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet., PMID:22106289
Mediator subunits: gene expression pattern, a novel transcript identification and nuclear localization in human endothelial progenitor cells., PMID:20493979
Secretion of the Streptomyces tyrosinase is mediated through its trans-activator protein, MelC1., PMID:1400329
For research use only. Not for human or drug use.
