Catalog No.
YHK63001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser86-Ser176
Predicted molecular weight
22.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96CA5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BIRC7, p30-Livin, Melanoma inhibitor of apoptosis protein, LIVIN, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Truncated livin, RNF50, KIAP, Livin, RING-type E3 ubiquitin transferase BIRC7, RING finger protein 50, tLivin, MLIAP, ML-IAP
Placental transcriptome reveals the placental brain axis genes and pathways of gestational diabetes mellitus (GDM) affecting offspring neurodevelopment., PMID:40298873
Silencing Livin gene expression by RNA interference enhanced the chemotherapeutic sensitivity of drug-resistant osteosarcoma cells to doxorubicin., PMID:40121921
Specific Targeting of Zinc Transporter LIV-1 with Immunocytokine Containing Anti-LIV-1 VHH and Human IL-2 and Evaluation of its In vitro Antitumor Activity., PMID:38482625
Livin expression promotes keratinocyte release of inflammatory mediators in psoriasis., PMID:38332513
Livin is protective in UVB-induced skin photodamage by regulating keratinocyte activation and inflammatory responses., PMID:38332512
Dendritic cells infected with recombinant adenoviral vector encoding mouse fibroblast activation protein-α and human livin α exert an antitumor effect against Lewis lung carcinoma in mice., PMID:37773704
RNA-seq reveals novel mechanistic targets of Livin in bladder cancer., PMID:36855119
Influence of Perinatal Factors on Gene Expression of IAPs Family and Main Factors of Pluripotency: OCT4 and SOX2 in Human Breast Milk Stem Cells-A Preliminary Report., PMID:36768802
Comparative transcriptomic analysis revealed changes in multiple signaling pathways involved in protein degradation in the digestive gland of Mytilus coruscus during high-temperatures., PMID:36731219
The clinicopathological and prognostic significances of IGF-1R and Livin expression in patients with colorectal cancer., PMID:35931997
Fisetin Deters Cell Proliferation, Induces Apoptosis, Alleviates Oxidative Stress and Inflammation in Human Cancer Cells, HeLa., PMID:35163629
Detection of Melanogenesis and Anti-Apoptosis-Associated Melanoma Factors: Array CGH and PPI Mapping Integrating Study., PMID:34749602
ADORA2A-AS1 Restricts Hepatocellular Carcinoma Progression via Binding HuR and Repressing FSCN1/AKT Axis., PMID:34733789
Integrative Analyses of Genes Associated With Right Ventricular Cardiomyopathy Induced by Tricuspid Regurgitation., PMID:34603374
A Pan-Cancer Analysis of the BIRC Gene Family and Its Association with Prognosis, Tumor Microenvironment, and Therapeutic Targets., PMID:34587434
Livin/BIRC7 gene expression as a possible diagnostic biomarker for endometrial hyperplasia and carcinoma., PMID:34568983
Tumor immune microenvironment of primary colorectal adenocarcinomas metastasizing to the liver or lungs., PMID:34351649
Livin in synergy with Ras induces and sustains corticosteroid resistance in the airway mucosa., PMID:34131408
RAG1 co-expression signature identifies ETV6-RUNX1-like B-cell precursor acute lymphoblastic leukemia in children., PMID:33987955
The Curcumin Analog EF24 is Highly Active Against Chemotherapy- Resistant Melanoma Cells., PMID:33655859
Inhibitor of apoptosis protein Livin promotes tumor progression and chemoradioresistance in human anaplastic thyroid cancer., PMID:33649820
Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin., PMID:33465114
BIRC7 and STC2 Expression Are Associated With Tumorigenesis and Poor Outcome in Extrahepatic Cholangiocarcinoma., PMID:33234031
Novel targeted mtLivin nanoparticles treatment for disseminated diffuse large B-cell lymphoma., PMID:33128043
Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers., PMID:33105831
125I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts., PMID:33059701
The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma., PMID:32928920
Huaier Granule Combined with Tegafur Gimeracil Oteracil Potassium Promotes Stage IIb Gastric Cancer Prognosis and Induces Gastric Cancer Cell Apoptosis by Regulating Livin., PMID:32724797
Methylation-mediated miR-214 regulates proliferation and drug sensitivity of renal cell carcinoma cells through targeting LIVIN., PMID:32395888
Oncostatin M upregulates Livin to promote keratinocyte proliferation and survival via ERK and STAT3 signalling pathways., PMID:32359099
The dual role of BI 2536, a small-molecule inhibitor that targets PLK1, in induction of apoptosis and attenuation of autophagy in neuroblastoma cells., PMID:32231733
A novel role for Livin in the response to ultraviolet B radiation and pterygium development., PMID:32124942
Inhibition of livin overcomes radioresistance in nasopharyngeal carcinoma cells., PMID:32119704
BIRC7 promotes epithelial-mesenchymal transition and metastasis in papillary thyroid carcinoma through restraining autophagy., PMID:32064154
Comprehensive molecular characterization of inhibitors of apoptosis proteins (IAPs) for therapeutic targeting in cancer., PMID:31964418
Association of expression of p53, livin, ERCC1, BRCA1 and PARP1 in epithelial ovarian cancer tissue with drug resistance and prognosis., PMID:31902551
MiR-512-3p regulates malignant tumor behavior and multi-drug resistance in breast cancer cells via targeting Livin., PMID:31777256
Livin promotes colon cancer progression by regulation of H2A.XY39ph via JMJD6., PMID:31445935
High expression of Livin serves as a predictive indicator for parotid gland tumors., PMID:31298372
Inhibitor of Apoptosis Proteins Determines Glioblastoma Stem-Like Cell Fate in an Oxygen-Dependent Manner., PMID:30920104
Expression of antiapoptotic proteins livin and survivin in pediatric AML patients, as prognostic markers., PMID:30588872
High BIRC7 Expression Might Be an Independent Prognostic Indicator of Poor Recurrence-Free Survival in Patients With Prostate Cancer., PMID:30376767
MicroRNA-23a induces apoptosis of hepatocarcinoma cell line MHCC97H via down-regulating KIAP: a mechanism study., PMID:30280770
Correlation between the methylation of LIVIN gene and the pathogenesis of bone tumor., PMID:30004566
Concomitant modulation of PTEN and Livin in gastric cancer treatment., PMID:29436592
The inhibitor of apoptosis protein livin is upregulated in psoriasis vulgaris., PMID:29265512
[Expression of Apoptosis-related Protein Livin and Caspase-3 in Diffuse Large B Cell Lymphoma and Its Clinical Significance]., PMID:29262894
Livin promotes the progression and metastasis of breast cancer through the regulation of epithelial‑mesenchymal transition via the p38/GSK3β pathway., PMID:29039608
Transfection with Livin and Survivin shRNA inhibits the growth and proliferation of non‑small cell lung cancer cells., PMID:28901499
miR-198-induced upregulation of Livin may be associated with the prognosis and contribute to the oncogenesis of lung adenocarcinoma., PMID:28765921
For research use only. Not for human or drug use.
