Catalog No.
YHB32601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser175
Predicted molecular weight
21.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O75840
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Krueppel-like factor 7, UKLF, KLF7, Ubiquitous krueppel-like factor
Krüppel like factor 7 regulates mitochondrial dynamics balance in myocardial infarction., PMID:40346382
Transcriptional Regulators in the Cerebellum in Chronic Schizophrenia: Novel Possible Targets for Pharmacological Interventions., PMID:40332239
KLF7-regulated ITGA2 as a therapeutic target for inhibiting oral cancer stem cells., PMID:40316546
Research and progress of microRNA-136 in metastatic tumors., PMID:40104500
The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression., PMID:39923113
Understanding the role of potential biomarkers in attenuating multiple sclerosis progression via multiomics and network-based approach., PMID:39700118
Alpha-lipoic acid targets KLF7 expression to inhibit cervical cancer progression., PMID:39696984
KLF7 Promotes Hepatocellular Carcinoma Progression Through Regulating SLC1A5-Mediated Tryptophan Metabolism., PMID:39648156
2q33 Deletions Underlying Syndromic and Non-syndromic CTLA4 Deficiency., PMID:39578275
To explore the protective effect and mechanism of KLF7 overexpression on retinal ganglion cells after optic nerve crush in mice., PMID:39513284
Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion., PMID:39333103
Hypoxic preconditioning-engineered bone marrow mesenchymal stem cell-derived exosomes promote muscle satellite cell activation and skeletal muscle regeneration via the miR-210-3p/KLF7 mechanism., PMID:39306891
Newborn adiposity is associated with cord blood DNA methylation at IGF1R and KLF7., PMID:39165088
KLF7 enhances the invasion and migration of colorectal cancer cells via the miR-139-5p/TPD52 axis., PMID:39097779
USP7 alleviates neuronal inflammation and apoptosis in spinal cord injury via deubiquitinating NRF1/KLF7 axis., PMID:39007840
Comparative analysis of Krüppel-like factors expression in the retinas of zebrafish and mice during development and after injury., PMID:38964422
KLF7 promotes neuroblastoma differentiation through the GTPase signaling pathway by upregulating neuroblast differentiation-associated protein AHNAKs and glycerophosphodiesterase GDPD5., PMID:38924469
UKLF/PCBP2 axis governs the colorectal cancer development by transcriptionally activating SLC39A4., PMID:38768927
E2F transcription factor 5, a new regulator in adipogenesis to mediate the role of Krüppel-like factor 7 in chicken preadipocyte differentiation and proliferation., PMID:38688194
KLF7 regulates super-enhancer-driven IGF2BP2 overexpression to promote the progression of head and neck squamous cell carcinoma., PMID:38443991
Long noncoding RNA expression in acute lymphoblastic leukemia: A systematic review., PMID:38341118
Cytotoxic and epigenetic effects of berberine-loaded chitosan/pectin nanoparticles on AGS gastric cancer cells: Role of the miR-185-5p/KLF7 axis, DNMTs, and global DNA methylation., PMID:38253156
Palmitic acid-activated GPRs/KLF7/CCL2 pathway is involved in the crosstalk between bone marrow adipocytes and prostate cancer., PMID:38221626
Resveratrol attenuates high glucose-induced inflammation and improves glucose metabolism in HepG2 cells., PMID:38212345
miR-520f-3p blocks MNNG-induced gastric precancerous lesions via the KLF7/NFκB pathway., PMID:38184286
KLF7 promotes colon adenocarcinoma progression through the PDGFB signaling pathway., PMID:38164176
The kruppel-like factor (KLF) family, diseases, and physiological events., PMID:38000704
Modulation of Krüppel-like factors (KLFs) interaction with their binding partners in cancers through acetylation and phosphorylation., PMID:37992989
The active phthalate metabolite, DHEP, induces proliferation and metastasis of prostate cancer cells via upregulation of β-catenin and downregulation of KLF7., PMID:37734194
HMGB1-mediated elevation of KLF7 facilitates hepatocellular carcinoma progression and metastasis through upregulating TLR4 and PTK2., PMID:37554278
Krüppel-like factor 7 deficiency disrupts corpus callosum development and neuronal migration in the developing mouse cerebral cortex., PMID:37401095
KLF7 promotes adipocyte inflammation and glucose metabolism disorder by activating the PKCζ/NF-κB pathway., PMID:37342904
Analysis of KLF7 and KLF5 transcription factors gene variants in coronary artery disease., PMID:37268267
Molecular function of Krüppel-like factor 7 in biology., PMID:37227154
Caprylic Acid (FFA C8:0) promotes the progression of prostate cancer by up-regulating G protein-coupled receptor 84/ Krüppel-like factor 7., PMID:37170248
[Overexpression of chicken Klf2 promotes klf7 transcription and inhibits adipocyte differentiation]., PMID:37154331
AHNAK, regulated by the OSM/OSMR signaling, involved in the development of primary localized cutaneous amyloidosis., PMID:37100691
Promotion of colorectal cancer by transcription factor BHLHE40 involves upregulation of ADAM19 and KLF7., PMID:36890812
The KLF7/PFKL/ACADL axis modulates cardiac metabolic remodelling during cardiac hypertrophy in male mice., PMID:36810848
Circular hsa_circ_0020377 regulates KLF7 by targeting miR-194-5p to facilitate tumor cell malignant behaviors and glycolysis in oral squamous cell carcinoma progression., PMID:36717528
PU.1 interacts with KLF7 to suppress differentiation and promote proliferation in chicken preadipocytes., PMID:36647727
Krüppel-like Factor 7 inhibits proliferation and migration of pulmonary smooth muscle cells via p21 activation., PMID:36566916
Long non-coding RNA XIST negatively regulates thoracic aortic aneurysm cell proliferation by targeting the miR-193a-5p/KLF7 axis., PMID:36495497
Genome-wide survey identifies TNNI2 as a target of KLF7 that inhibits chicken adipogenesis via downregulating FABP4., PMID:36410687
Inhibition of microRNA-19a-3p alleviates the neuropathic pain (NP) in rats after chronic constriction injury (CCI) via targeting KLF7., PMID:36334791
KLF7 promotes preadipocyte proliferation via activation of the Akt signaling pathway by Cis-regulating CDKN3., PMID:36269137
LncRNA NUTM2A-AS1 aggravates the progression of hepatocellular carcinoma by activating the miR-186-5p/KLF7-mediated Wnt/beta-catenin pathway., PMID:36242728
Krüppel-like factor 7 influences translation and pathways involved in ribosomal biogenesis in breast cancer., PMID:36192788
Krüppel-like factors family regulation of adipogenic markers genes in bovine cattle adipogenesis., PMID:35988893
Expression and Clinical Significance of Serum Krüppel-Like Factor 7 (KLF7) in NSCLC Patients., PMID:35936369