Catalog No.
YHF94401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys2-Glu86
Predicted molecular weight
21.69 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02535
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ID3, 1R21, BHLHB25, bHLHb25, Class B basic helix-loop-helix protein 25, Inhibitor of differentiation 3, DNA-binding protein inhibitor ID-3, Inhibitor of DNA binding 3, HEIR1, Helix-loop-helix protein HEIR-1, ID-like protein inhibitor HLH 1R21
Biological characteristics of spontaneous ovarian cancer in Microtusfortis., PMID:40457786
A Data-Driven Approach to Assessing Hepatitis B Mother-to-Child Transmission Risk Prediction Model: Machine Learning Perspective., PMID:40409750
Id2 transcriptional repressor promotes retinal Müller glial cell fate choice by increasing Notch activity., PMID:40398096
Reprogramming of skin fibroblasts by 3D spheroid culture promotes peripheral nerve regeneration via the ID3/semaphorin7a pathway., PMID:40213860
ID3 enhances PD-L1 expression by restructuring MYC to promote colorectal cancer immune evasion., PMID:40208940
Targeting COPA to Enhance Erdafitinib Sensitivity in FGFR-Altered Bladder Cancer., PMID:40112217
PADI4 facilitates stem-like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma., PMID:40078091
Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression., PMID:39888981
AMH protects the ovary from doxorubicin by regulating cell fate and the response to DNA damage., PMID:39874288
Pathophysiological Features of Remodeling in Vascular Diseases: Impact of Inhibitor of DNA-Binding/Differentiation-3 and Estrogenic Endocrine Disruptors., PMID:39846697
ID3 promotes erythroid differentiation and is repressed by a TAL1-PRMT6 complex., PMID:39716491
ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia., PMID:39676870
Genomic differences of patients with hematologic malignancies in different age groups., PMID:39643631
[Hepatic T cell subtypes and functional analysis among alveolar echinococcosis patients using single-cell RNA sequencing]., PMID:39623989
AS03-adjuvanted H5N1 vaccine enhances immune response by modulating NR4A1, SDC1, ID3 genes, and reducing cortisol., PMID:39569615
Upregulation of inhibitor of DNA binding 1 and 3 is important for efficient thermogenic response in human adipocytes., PMID:39550428
Generation of ID1/3 knockout human embryonic stem cell lines (WAe009-A-2A and WAe009-A-2B) derived from H9 using CRISPR/Cas9., PMID:39342788
Functionally redundant roles of ID family proteins in spermatogonial stem cells., PMID:39332405
Breaking new ground: Unraveling the USP1/ID3/E12/P21 axis in vascular calcification., PMID:39326697
Gene regulatory mechanisms of T cell exhaustion in diffuse large B cell lymphoma based on single-cell transcriptome data., PMID:39307100
Strong Activation of ID1, ID2, and ID3 Genes Is Coupled with the Formation of Vasculogenic Mimicry Phenotype in Melanoma Cells., PMID:39273240
Induced pluripotent stem cell-derived neural stem cells promote bone formation in mice with calvarial defects., PMID:39241820
The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis., PMID:39216001
Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587
Assessment of ID family proteins expression in colorectal cancer of Iraqi patients., PMID:39001993
E proteins control the development of NKγδT cells through their invariant T cell receptor., PMID:38871720
AMH protects the ovary from doxorubicin by regulating cell fate and the response to DNA damage., PMID:38826466
Single-cell RNA-seq reveals novel interaction between muscle satellite cells and fibro-adipogenic progenitors mediated with FGF7 signalling., PMID:38751367
Clinical implications of CSF-ctDNA positivity in newly diagnosed diffuse large B cell lymphoma., PMID:38750139
Development of a machine learning-based model to predict prognosis of alpha-fetoprotein-positive hepatocellular carcinoma., PMID:38741163
Mimicking the cellular environment does not cause monocyte-derived macrophages to become phenotypically similar to Kupffer cells., PMID:38629182
SOX11 expression is restricted to EBV-negative Burkitt lymphoma and is associated with molecular genetic features., PMID:38620074
Endothelial Cell Flow-Mediated Quiescence Is Temporally Regulated and Utilizes the Cell Cycle Inhibitor p27., PMID:38602102
ID factors regulate the ability of Müller glia to become proliferating neurogenic progenitor-like cells., PMID:38515287
ID3 is a novel target gene of p53 and modulates lung cancer cell metastasis., PMID:38513475
Silibinin is a suppressor of the metastasis-promoting transcription factor ID3., PMID:38484626
Unveiling the antitumor function of ID3 in liver macrophages., PMID:38429457
The nuclear factor ID3 endows macrophages with a potent anti-tumour activity., PMID:38326607
ALDOA coordinates PDE3A through the β-catenin/ID3 axis to stimulate cancer metastasis and M2 polarization in lung cancer with EGFR mutations., PMID:38244313
Id3 keeps the PD-1 checkpoint in check in GVHD., PMID:38206642
Identification and validation of plasma AGRN as a novel diagnostic biomarker of hepatitis B Virus-related chronic hepatitis and liver fibrosis/cirrhosis., PMID:38197199
Pre-treatment of canine plasma with heat, rather than acid, efficiently enhances Dirofilaria immitis antigen detection., PMID:38115152
Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke., PMID:38112574
ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors., PMID:38060444
The genetic landscape of histologically transformed marginal zone lymphomas., PMID:37941429
Effect of Hyperbaric Oxygen and Inflammation on Human Gingival Mesenchymal Stem/Progenitor Cells., PMID:37887323
Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD., PMID:37871574
Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosis., PMID:37790548
Changes in Expression in BMP2 and Two Closely Related Genes in Guinea Pig Retinal Pigment Epithelium during Induction and Recovery from Myopia., PMID:37759773
Inhibitor of DNA Binding Protein 3 (ID3) and Nuclear Respiratory Factor 1 (NRF1) Mediated Transcriptional Gene Signatures are Associated with the Severity of Cerebral Amyloid Angiopathy., PMID:37668961
For research use only. Not for human or drug use.
