Catalog No.
YHE06101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met258-Ala325
Predicted molecular weight
20.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P34969
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
5-hydroxytryptamine receptor 7, 5-HT-X, HTR7, 5-HT7, Serotonin receptor 7, 5-HT-7
Restraint Stress Disrupted Intestinal Homeostasis via 5-HT/HTR7/Wnt/β-Catenin/NF-kB Signaling., PMID:40362261
Neurotransmitter 5-HT Further Promotes LL-37-Induced Rosacea-like Inflammation Through HTR3A., PMID:40243950
Daily acute intermittent hypoxia elicits age & sex-dependent changes in molecules regulating phrenic motor plasticity., PMID:40204197
Characterization of the Molecular Mechanisms Underlying Lurasidone-Induced Acute Manic Episodes in Bipolar Depression: A Network Pharmacology and Molecular Docking Approach., PMID:40202273
Serotonin 3 receptor antagonism reduces angiotensin II-induced abdominal aortic aneurysms: Contribution of periaortic fat-derived serotonin., PMID:40023595
Exploring the Immune-Related Molecular Mechanisms Underlying the Comorbidity of Temporal Lobe Epilepsy and Major Depressive Disorder through Integrated Data Set Analysis., PMID:39976098
Exploring therapeutic potential of Bacopa monnieri bioactive compounds against Alzheimer's and Parkinson's diseases., PMID:39959708
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches., PMID:39938415
Identification of potential drug targets for four site-specific cancers by integrating human plasma proteome with genome., PMID:39933395
Association between 5-HTRs gene polymorphism and alcohol use disorder in Han males from Yunnan, China., PMID:39889837
Activation of 5-HT7 receptors in the mouse dentate gyrus does not affect theta-burst-induced plasticity at the perforant path synapse., PMID:39487932
Mouse enteric neurons control intestinal plasmacytoid dendritic cell function via serotonin-HTR7 signaling., PMID:39455564
Tryptophan-rich diet and its effects on Htr7+ Tregs in alleviating neuroinflammation and cognitive impairment induced by lipopolysaccharide., PMID:39334486
The interplay of serotonin 5-HT1A and 5-HT7 receptors in chronic stress., PMID:39279505
Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau protein., PMID:39027123
A genetic variant study of bortezomib-induced peripheral neuropathy in Chinese multiple myeloma patients., PMID:38686049
Effect of Short Photoperiod on Behavior and Brain Plasticity in Mice Differing in Predisposition to Catalepsy: The Role of BDNF and Serotonin System., PMID:38473717
Exploratory research on genetic polymorphisms associated with positive empathy and trait forgivingness among the Japanese., PMID:38131174
The impact of Akkermansia muciniphila and its extracellular vesicles in the regulation of serotonergic gene expression in a small intestine of mice., PMID:37797929
Identification, characterization, and transcription of serotonin receptors in rainbow trout (Oncorhynchus mykiss) in response to bacterial infection and salinity changes., PMID:37481174
Serotonin Receptors and Acetylcholinesterase Gene Expression Alternations: The Potential Value on Tumor Microenvironment of Gastric Cancer., PMID:37231904
5-Hydroxytryptophan inhibits β-casein biosynthesis and promotes goat mammary epithelial cell apoptosis through the JAK2/STAT5a axis and the HTR7., PMID:36964762
The prognostic signature based on glycolysis-immune related genes for acute myeloid leukemia patients., PMID:36868006
Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT2A receptors in the ventral hippocampus., PMID:36846570
Habenula as a Possible Target for Treatment-Resistant Depression Phenotype in Wistar Kyoto Rats., PMID:36344870
Targeting the brain 5-HT7 receptor to prevent hypomyelination in a rodent model of perinatal white matter injuries., PMID:36335540
Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1., PMID:36006564
In Vitro Generation of Brain Regulatory T Cells by Co-culturing With Astrocytes., PMID:35911740
Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer's and Parkinson's diseases as druggable targets through Withania somnifera bioactives: an in silico study., PMID:35491707
5-HT7 receptors expressed in the mouse parafacial region are not required for respiratory chemosensitivity., PMID:35385139
5-HT7 receptors in Alzheimer's disease., PMID:34555475
5-HT7 receptors enhance inhibitory synaptic input to principal neurons in the mouse basal amygdala., PMID:34481835
HTR7 promotes laryngeal cancer growth through PI3K/AKT pathway activation., PMID:34164474
MassARRAY multigene screening combined with LDL-C and sdLDL-C detection for more favorable outcomes in type 2 diabetes mellitus therapy., PMID:33731122
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death., PMID:33461384
Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia., PMID:33048949
Implication of 5-HT7 receptor in prefrontal circuit assembly and detrimental emotional effects of SSRIs during development., PMID:32688364
Comparative Transcriptome Analysis Suggests Key Roles for 5-Hydroxytryptamlne Receptors in Control of Goose Egg Production., PMID:32331314
Signatures of altered DNA methylation gene expression after central and peripheral nerve injury., PMID:31691285
Serotonin receptor oligomerization regulates cAMP-based signaling., PMID:31371490
Regulatory T Cells: Pathophysiological Roles and Clinical Applications., PMID:31353330
Association of SLCO1B1 and ABCB1 Genetic Variants with Atorvastatin-induced Myopathy in Patients with Acute Ischemic Stroke., PMID:31298164
Creation of the 5-hydroxytryptamine receptor 7 knockout rat as a tool for cardiovascular research., PMID:31125290
Tissue regulatory T cells and neural repair., PMID:30893423
A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression., PMID:30874608
MiRNA-29a modulates visceral hyperalgesia in irritable bowel syndrome by targeting HTR7., PMID:30827505
Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery., PMID:30602786
Intraspinal Grafting of Serotonergic Neurons Modifies Expression of Genes Important for Functional Recovery in Paraplegic Rats., PMID:30147717
The effect of chronic stimulation of serotonin receptor type 7 on recognition, passive avoidance memory, hippocampal long-term potentiation, and neuronal apoptosis in the amyloid β protein treated rat., PMID:29637287
Activation of 5-HT7 receptor by administration of its selective agonist, LP-211, modifies explorative-curiosity behavior in rats in two paradigms which differ in visuospatial parameters., PMID:29392842
For research use only. Not for human or drug use.
