Catalog No.
YHF89701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp353-Arg446
Predicted molecular weight
22.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q01844
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RNA-binding protein EWS, EWS oncogene, EWS, EWSR1, Ewing sarcoma breakpoint region 1 protein
EWSR1 Rearrangements in Basaloid Neoplasms With Adnexal Differentiation., PMID:40511965
METTL3-mediated SNHG1 m6A modification promotes proliferation and migration through transcriptional regulation of WDR74 in osteosarcoma., PMID:40510136
[Cytokeratin (pan)-positive EWSR1/FUS::CREB fusion malignant tumor in abdominopelvic cavity: a clinicopathological and molecular analysis of four cases]., PMID:40494767
Histone deacetylase inhibitors target DNA replication regulators and replication stress in Ewing sarcoma cells., PMID:40478628
Intracranial mesenchymal tumor with EWSR1-rearrangement (FET::CREB family): A case series with clinico-radiological and pathological correlation and review of literature., PMID:40454531
Primary spinal cord astroblastoma: a case report and systematic review of the literature detailing management and understanding histopathological, epigenetic, and molecular analysis., PMID:40446351
Extraenteric Malignant Gastrointestinal Neuroectodermal Tumor of the Neck: A Diagnostic Challenge., PMID:40429661
Establishment and characterization of NCC-MLPS4-C1: a novel patient-derived cell line of myxoid liposarcoma., PMID:40418421
A peculiar mimicker of gastro-entero-pancreatic neuroendocrine tumors: Malignant Gastrointestinal Neuroectodermal Tumor - literature review and one case report., PMID:40416581
Glioneuronal tumors PATZ1-fused: clinico-molecular and DNA methylation signatures for a variety of morphological and radiological profiles., PMID:40413488
Emerging connections: Poly(ADP-ribose), FET proteins and RNA in the regulation of DNA damage condensates., PMID:40381401
Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain., PMID:40377985
RNA-binding protein gene NOP58 exhibits crucial prognostic and therapeutic value in Ewing sarcoma., PMID:40369667
Clinicopathologic and Molecular Characterization of SMARCB1-Deificient Sinonasal Carcinomas -A Systematic Study from a Single Institution Cohort., PMID:40366517
Diagnostic Utility of NKX3.1 in Mesenchymal Chondrosarcoma on Needle Biopsy: A Case Report of a Supraclavicular Soft Tissue Mass with Literature Review., PMID:40323235
High Tau expression correlates with reduced invasion and prolonged survival in Ewing sarcoma., PMID:40319030
[Adamantinoma-like Ewing sarcoma of duodenal ameoblastoma with EWSR1::ERG gene fusion: report of a case]., PMID:40302590
Purification of Low-Complexity Domain Proteins FUS, EWSR1, and Their Fusions., PMID:40285687
At the crossroad between Ewing sarcoma and neuroblastoma: a report of two cases of Ewing sarcoma with post treatment neuroblastoma-like differentiation., PMID:40269875
The self-renewal function of Oct-4 can be replaced by the EWS-Oct-4 fusion protein in embryonic stem cells., PMID:40251420
Ewing sarcoma of the rib with a rare PTEN mutation., PMID:40245483
Primary Pulmonary Myxoid Sarcoma Located in the Left Lung Parenchyma: Case Report with a Review of Literature., PMID:40242429
LOXHD1 is an oncofusion-regulated antigen of ewing sarcoma., PMID:40234527
Utility of Protein Kinase C Beta II Immunohistochemistry in Differential Diagnosis of Ewing Sarcoma., PMID:40230184
(GGAA)3-Based TF-PROTACs Enable Targeted Degradation of ETV6 to Inhibit Ewing Sarcoma Growth., PMID:40215343
EWSR1::SSX1 Fusion-Driven Synovial Sarcoma: A Case Presentation and Review of the Literature., PMID:40207937
"Putting the cart before the horse": an update on promiscuous gene fusions in soft tissue tumors., PMID:40205020
Clinicopathologic and molecular characterization of primitive neuroectodermal tumors (PNET) in the female genital tract: a retrospective study of 8 cases., PMID:40189027
Pathologic and genomic characteristics of myoepithelioma-like tumor of the vulvar region: three case reports., PMID:40188333
The TAAR1 Agonist PCC0105004 Regulates Amygdala Synaptic Plasticity to Alleviate Anxiety-Like Behaviors in Rats., PMID:40186385
Characterization of a novel sarcoma cell line with an EWSR1::POU2AF3 fusion., PMID:40134582
Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites., PMID:40131773
Primary Ewing sarcoma of renal origin with tumor thrombus into inferior vena cava: a case report., PMID:40102995
RNF114 Interacts with EWSR1 to Regulate VEGFR2 in HER2-positive Breast Cancer., PMID:40092691
Targeted inactivation of EWSR1 : : FLI1 gene in Ewing sarcoma via CRISPR/Cas9 driven by an Ewing-specific GGAA promoter., PMID:40089636
YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1-mediated reprogramming of bone mesenchymal stem cells., PMID:40080499
EWSR1::CREM Fusion in a Pediatric Patient With Testicular Leydig Cell Tumor., PMID:40072299
EWS-RNA Binding Protein 1: Structural Insights into Ewing Sarcoma by Conformational Dynamics Investigations., PMID:40070334
EWSR1::BEND2 fusion sarcoma in bone: a report of two rare cases., PMID:40042664
A Cutaneous Vascular Neoplasm With an EWSR1-NFATC2 Translocation-Contributing to the Spectrum of Vascular Lesions Characterized by NFATC-Related Fusions., PMID:40037835
[Angiomatoid fibrous histiocytoma: a clinicopathological analysis of 14 cases]., PMID:40032419
Intracardiac myoepithelial carcinoma with EWSR1::KLF15 fusion: A rare case of pediatric primary cardiac malignancy., PMID:40021072
A MAZ::NCOA2 Subcutaneous Small Round Cell Sarcoma of Infancy With Diffuse S100/SOX10 Positivity: A Novel Entity., PMID:39985329
Sinonasal EWSR1::POU2AF3 sarcoma: a case report and literature review., PMID:39982522
Decoding phase separation of prion-like domains through data-driven scaling laws., PMID:39937084
Refined culture conditions with increased physiological relevance uncover oncogene-dependent metabolic signatures in Ewing sarcoma spheroids., PMID:39922188
High expression level of ERBB2 and efficacy of trastuzumab deruxtecan in desmoplastic small round cell tumour: a monocentric case series report., PMID:39921935
The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma., PMID:39894896
Rhabdomyosarcoma With EWSR1::NF2 Gene Fusion: A Case Report Potentially Expanding Its Genetic Spectrum., PMID:39873201
Non-myxoid solid variant of extraskeletal myxoid chondrosarcoma: An underrecognized subtype., PMID:39828007
For research use only. Not for human or drug use.
