Catalog No.
YHD33801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp2-Ser87
Predicted molecular weight
22.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19419
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ELK1, ETS domain-containing protein Elk-1
The impact of mechanical unloading on the gut microbiota and the mitigating role of butyrate in bone loss., PMID:40424649
ELK1 inhibition alleviates amyloid pathology and memory decline by promoting the SYVN1-mediated ubiquitination and degradation of PS1 in Alzheimer's disease., PMID:40307574
Structural basis of human Mediator recruitment by the phosphorylated transcription factor Elk-1., PMID:40263353
STAT-3, ELK-1, and c- Jun contributes IL-6 mediated ADAMTS-8 upregulation in colorectal cancer., PMID:39969607
CircMFN2/miR-361-3p/ELK1 feedback loop promotes glutaminolysis and the progression of hepatocellular carcinoma., PMID:39933635
Hsa_circRNA_000166 accelerates breast cancer progression via the regulation of the miR-326/ELK1 and miR-330-5p/ELK1 axes., PMID:39529543
Suppressing DUSP16 overexpression induced by ELK1 promotes neural progenitor cell differentiation in mouse models of Alzheimer's disease., PMID:39434411
EphA-Mediated Regulation of Stomatin Expression in Prostate Cancer Cells., PMID:39377541
Baicalein Inhibits Metastasis of Oral Squamous Cell Carcinoma Cells by Regulating ERK/ELK-1/Snail Signaling., PMID:38926116
Serum Response Factor Expression in Excess Permits a Dual Contractile-Proliferative Phenotype of Airway Smooth Muscle., PMID:38775474
Dysregulation of the Long Noncoding RNA X-Inactive-Specific Transcript Expression in Male Patients with Pulmonary Arterial Hypertension., PMID:38705381
Elk1 enhances inflammatory cell infiltration and exacerbates acute lung injury/acute respiratory distress syndrome by suppressing Fcgr2b transcription., PMID:38649840
Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation., PMID:38589882
High expression of RTEL1 predicates worse progression in gliomas and promotes tumorigenesis through JNK/ELK1 cascade., PMID:38532312
OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma., PMID:38483541
ELK1/MTOR/S6K1 Pathway Contributes to Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer., PMID:38397056
The nuclear factor ID3 endows macrophages with a potent anti-tumour activity., PMID:38326607
ANXA3 interference inactivates ERK/ELK1 pathway to mitigate inflammation and apoptosis in sepsis-associated acute lung injury., PMID:38310670
Mutant p53 and ELK1 co-drive FRA-1 expression to induce metastasis in breast cancer., PMID:37971884
Exploring dual effects of dinutuximab beta on cell death and proliferation of insulinoma., PMID:37802653
Guben Xiezhuo Decoction inhibits M1 polarization through the Raf1/p-Elk1 signaling axis to attenuate renal interstitial fibrosis., PMID:37716490
Aberrant expression of CKS2 induced by ELK1 contributes to malignant progression of pancreatic cancer., PMID:37642304
Role of ELK1 in regulating colorectal cancer progression: miR-31-5p/CDIP1 axis in CRC pathogenesis., PMID:37547727
ELK1/KIFC1 axis promotes breast cancer cell proliferation by regulating glutathione metabolism., PMID:37339943
Androgen receptor knockdown enhances prostate cancer chemosensitivity by down-regulating FEN1 through the ERK/ELK1 signalling pathway., PMID:37326412
Transcription factor ELK1 regulates the expression of histone 3 lysine 9 to affect developmental potential of porcine preimplantation embryos., PMID:37224706
Hsa_circ_0008500 inhibits apoptosis of adipose-derived stem cells under high glucose through hsa-miR-1273h-5p/ELK1 axis., PMID:37014014
The Small Molecule Antagonist KCI807 Disrupts Association of the Amino-Terminal Domain of the Androgen Receptor with ELK1 by Modulating the Adjacent DNA Binding Domain., PMID:36720643
A-Kinase Anchor Protein 95 Is Involved in ERK1/2-Elk-1 Signal Transduction in Colon Cancer., PMID:36691407
The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1., PMID:36575212
Comparative analysis of protein expression systems and PTM landscape in the study of transcription factor ELK-1., PMID:36528218
Circ_0022340 promotes colorectal cancer progression via HNRNPC/EBF1/SYT7 or miR-382-5p/ELK1 axis., PMID:36495510
ELK1-mediated YTHDF1 drives prostate cancer progression by facilitating the translation of Polo-like kinase 1 in an m6A dependent manner., PMID:36439881
BCL6 is regulated by the MAPK/ELK1 axis and promotes KRAS-driven lung cancer., PMID:36377663
ELK1 suppresses SYTL1 expression by recruiting HDAC2 in bladder cancer progression., PMID:36107384
Silencing circ_0074371 inhibits the progression of sepsis-induced acute kidney injury by regulating miR-330-5p/ELK1 axis., PMID:35994105
GPX4 suppresses ferroptosis to promote malignant progression of endometrial carcinoma via transcriptional activation by ELK1., PMID:35962333
ELK1-Induced upregulation of long non-coding TNK2-AS1 promotes the progression of acute myeloid leukemia by EZH2-mediated epigenetic silencing of CELF2., PMID:35941836
Identification of ELK1 interacting peptide segments in the androgen receptor., PMID:35781489
LncRNA 122049 suppresses apoptosis of renal tubular epithelial cells in ischemic AKI by targeting the miR-330-5p/ELK1 axis., PMID:35695811
Sirt7 associates with ELK1 to participate in hyperglycemia memory and diabetic nephropathy via modulation of DAPK3 expression and endothelial inflammation., PMID:35470010
The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy., PMID:35351142
Knockdown of lncRNA LINC00662 suppresses malignant behaviour of osteosarcoma cells via competition with miR-30b-3p to regulate ELK1 expression., PMID:35123530
T-cell activation decreases miRNA-15a/16 levels to promote MEK1-ERK1/2-Elk1 signaling and proliferative capacity., PMID:35085550
Highly-metastatic colorectal cancer cell released miR-181a-5p-rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment., PMID:35041299
ELK1 Promotes Epithelial-Mesenchymal Transition and the Progression of Lung Adenocarcinoma by Upregulating B7-H3., PMID:34970415
ELK1-induced up-regulation of KIF26B promotes cell cycle progression in breast cancer., PMID:34817735
Circ-PTPDC1 promotes the Progression of Gastric Cancer through Sponging Mir-139-3p by Regulating ELK1 and Functions as a Prognostic Biomarker., PMID:34803498
MicroRNA-150 and its target ETS-domain transcription factor 1 contribute to inflammation in diabetic photoreceptors., PMID:34704358
Peroxisome proliferator‑activated receptor β/δ regulates cerebral vasospasm after subarachnoid hemorrhage via modulating vascular smooth muscle cells phenotypic conversion., PMID:34664679
For research use only. Not for human or drug use.
