Catalog No.
YHE00801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly205-Glu291
Predicted molecular weight
22.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P32519
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ETS-related transcription factor Elf-1, E74-like factor 1, ELF1
ELF1-mediated transactivation of METTL3/YTHDF2 promotes nucleus pulposus cell senescence via m6A-dependent destabilization of E2F3 mRNA in intervertebral disc degeneration., PMID:40467575
Elf1 Deficiency Impairs Macrophage Development in Zebrafish Model Organism., PMID:40141178
Core transcriptional regulatory circuitry molecule ZNF217 promotes AML cell proliferation by up-regulating MYB., PMID:40083704
Transcription factor ELF-1 protects against colitis by maintaining intestinal epithelium homeostasis., PMID:40057592
ELF1's Role in Colorectal Cancer: Up-Regulating DCLK1 Expression to Propel Malignant Progression and Stemness Features., PMID:39973554
METTL14-mediated m6A methylation of pri-miR-5099 to facilitate cardiomyocyte pyroptosis in myocardial infarction., PMID:39939804
Identification of critical genes and drug repurposing targets in entorhinal cortex of Alzheimer's disease., PMID:39928227
Genetic insights into CRP levels in Indian adolescents: confirming adult genetic associations., PMID:39843866
Distinct genetic risk loci between biopsy-proven renal and non-renal lupus: a 10-year longitudinal cohort., PMID:39832277
Overexpression of ELF1 combined with MMP9 is associated with prognosis and tumor microenvironment in gastric cancer., PMID:39583246
ELF1 serves as a potential biomarker for the disease activity and renal involvement in systemic lupus erythematosus., PMID:39496744
Super-Enhancer-Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T-ALL Cell Growth and Survival., PMID:39454110
ETS Transcription Factors in Immune Cells and Immune-Related Diseases., PMID:39337492
ARL11 knockdown alleviates spinal cord injury by inhibiting neuroinflammation and M1 activation of microglia in mice., PMID:39307293
Elf1 promotes transcription-coupled repair in yeast by using its C-terminal domain to bind TFIIH., PMID:39043658
MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated Kinase ERK., PMID:39028853
Combination of computational techniques and RNAi reveal targets in Anopheles gambiae for malaria vector control., PMID:38968330
Modulation of angiopoietin-2 and Tie2: Organ specific effects of microvascular leakage and edema in mice., PMID:38723844
Integrative analysis of chromatin accessibility and transcriptome landscapes in the induction of peritoneal fibrosis by high glucose., PMID:38443979
Dietary steroids promote body weight growth and induce gametogenesis by increasing the expressions of genes related to cell proliferation of sea cucumber (Apostichopus japonicus)., PMID:38237259
Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair., PMID:38194460
Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA., PMID:37981206
Clinical features, epidemiology, and treatment of Shwachman-Diamond syndrome: a systematic review., PMID:37803383
ELF1/PRR11/ARP2/3 promoted trophoblast cells proliferation and motility in early pregnancy., PMID:37641376
Preservation of ∼12-h ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock., PMID:37324401
Preservation of ∼12-hour ultradian rhythms of gene expression of mRNA and protein metabolism in the absence of canonical circadian clock., PMID:37205336
TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid leukemia., PMID:37102302
Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs., PMID:37071125
Identification of Common Dysregulated Genes in COVID-19 and Hypersensitivity Pneumonitis: A Systems Biology and Machine Learning Approach., PMID:37062762
Intertwined Dysregulation of Ribosomal Proteins and Immune Response Delineates SARS-CoV-2 Vaccination Breakthroughs., PMID:37022180
Integrative network-based analysis on multiple Gene Expression Omnibus datasets identifies novel immune molecular markers implicated in non-alcoholic steatohepatitis., PMID:37008925
ELF1 suppresses autophagy to reduce cisplatin resistance via the miR-152-3p/NCAM1/ERK axis in lung cancer cells., PMID:36846943
Transcription Factor ELF1 Modulates Cisplatin Sensitivity in Prostate Cancer by Targeting MEIS Homeobox 2., PMID:36763086
Transcriptome-wide analysis reveals the coregulation of RNA-binding proteins and alternative splicing genes in the development of atherosclerosis., PMID:36720950
Elongation factor 1 is a component of the Arabidopsis RNA polymerase II elongation complex and associates with a subset of transcribed genes., PMID:36627730
Single-nucleus RNA and ATAC sequencing uncovers the molecular and cellular characteristics in the musk gland of Chinese forest musk deer (Moschus berezovskii)., PMID:36583723
Chemoproteomic profiling to identify activity changes and functional inhibitors of DNA-binding proteins., PMID:36356585
Systems-level identification of key transcription factors in immune cell specification., PMID:36156073
Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT., PMID:35981082
A nerve injury-specific long noncoding RNA promotes neuropathic pain by increasing Ccl2 expression., PMID:35775484
E74-like factor 1 contributes to nerve trauma-induced nociceptive hypersensitivity through transcriptionally activating matrix metalloprotein-9 in dorsal root ganglion neurons., PMID:35507368
Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity., PMID:35487911
LncRNA HOXD-AS1 affects proliferation and apoptosis of cervical cancer cells by promoting FRRS1 expression via transcription factor ELF1., PMID:34985386
Lnc5926 is essential for early embryonic development in goats through regulation of ZSCAN4 and EIF1AX., PMID:34954662
Transcriptomic Remodelling of Fetal Endothelial Cells During Establishment of Inflammatory Memory., PMID:34867995
A functionally divergent transcription elongation factor 1-like protein in Toxoplasma gondii., PMID:34820838
Identification of key molecular markers in epithelial ovarian cancer by integrated bioinformatics analysis., PMID:34794761
Modulation of STIM1 by a risk insertion/deletion polymorphism underlying genetics susceptibility to sudden cardiac death originated from coronary artery disease., PMID:34592581
Comprehensive Analysis of CD163 as a Prognostic Biomarker and Associated with Immune Infiltration in Glioblastoma Multiforme., PMID:34395626
A CpG island promoter drives the CXXC5 gene expression., PMID:34341443
For research use only. Not for human or drug use.
