Catalog No.
YHA86201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Thr330
Predicted molecular weight
38.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O60282
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Kinesin heavy chain isoform 5C, KIAA0531, KIF5C, Kinesin heavy chain neuron-specific 2, NKHC2
The gE/gI complex is necessary for kinesin-1 recruitment during alphaherpesvirus egress from neurons., PMID:39651860
Expanding the Molecular and Clinical Phenotype of Patients With De Novo Variants in KIF5C: A Six Patient Case Series., PMID:39503049
Role of hsa-miR-543-KIF5C/CALM3 pathway in neuron differentiation of embryonic mesenchymal stem cells., PMID:39444227
Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders., PMID:39033378
Identification of several lncRNA-mRNA pairs associated with marbling trait between Nanyang and Angus cattle., PMID:39014336
Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders., PMID:38585811
Synaptically-targeted long non-coding RNA SLAMR promotes structural plasticity by increasing translation and CaMKII activity., PMID:38538603
A novel in-frame deletion in KIF5C gene causes infantile onset epilepsy and psychomotor retardation., PMID:38525108
The importance of routine genetic testing in pediatric epilepsy surgery., PMID:38366963
RNA sequencing reveals differential long noncoding RNA expression profiles in bacterial and viral meningitis in children., PMID:38347610
A multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A., PMID:38309508
Solution NMR assignments and structure for the dimeric kinesin neck domain., PMID:37861970
Insect Cell-Based Expression of Cytoskeletal Motor Proteins for Single-Molecule Studies., PMID:37824000
UNC-116 and UNC-16 function with the NEKL-3 kinase to promote axon targeting., PMID:37756604
Integrated transcriptome and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during gestation and lactation., PMID:37690569
Microtubule-associated septin complexes modulate kinesin and dynein motility with differential specificities., PMID:37495111
LncRNA ZNF667-AS1 Targets miR-523-3p/KIF5C Axis to Hinder Colon Cancer Progression., PMID:37322260
Overexpression of MicroRNA-155 aggravates pulpitis by targeting kinesin superfamily Proteins-5C based on illumina high-throughput sequencing., PMID:37070646
Generation of recombinant and chickenized scFv versions of an anti-kinesin monoclonal antibody H2., PMID:37036074
SLAMR, a synaptically targeted lncRNA, facilitates the consolidation of contextual fear memory., PMID:36993323
Integrated analysis of transcription factor-mRNA-miRNA regulatory network related to immune characteristics in medullary thyroid carcinoma., PMID:36713370
Involvement of miR-135a-5p Downregulation in Acute and Chronic Stress Response in the Prefrontal Cortex of Rats., PMID:36675068
Tubb3 expression levels are sensitive to neuronal activity changes and determine microtubule growth and kinesin-mediated transport., PMID:36309617
Abnormal course of the corticospinal tracts in KIF5C-related encephalopathy., PMID:36122673
HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury., PMID:36048753
Dominantly acting KIF5B variants with pleiotropic cellular consequences cause variable clinical phenotypes., PMID:36018820
A kinesin-1 variant reveals motor-induced microtubule damage in cells., PMID:35504282
KIF5C deficiency causes abnormal cortical neuronal migration, dendritic branching, and spine morphology in mice., PMID:34966180
Predicting signaling pathways regulating demyelination in a rat model of lithium-pilocarpine-induced acute epilepsy: A proteomics study., PMID:34742844
Deletion of Kif5c Does Not Alter Prion Disease Tempo or Spread in Mouse Brain., PMID:34372599
A kinesin 1-protrudin complex mediates AMPA receptor synaptic removal during long-term depression., PMID:34348158
Case of multifocal glioblastoma with four fusion transcripts of ALK, FGFR2, NTRK2, and NTRK3 genes stresses the need for tumor tissue multisampling for transcriptomic analysis., PMID:34341009
Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation., PMID:34260917
Myelination defects in the medial prefrontal cortex of Fkbp5 knockout mice., PMID:33410216
Phenotype description in KIF5C gene hot-spot mutations responsible for malformations of cortical development (MCD)., PMID:32562872
Deletion of the Pseudorabies Virus gE/gI-US9p complex disrupts kinesin KIF1A and KIF5C recruitment during egress, and alters the properties of microtubule-dependent transport in vitro., PMID:32511265
Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory., PMID:31961321
Reduced miR-203 predicts metastasis and poor survival in esophageal carcinoma., PMID:31844033
The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C., PMID:31757889
A novel strategy to visualize vesicle-bound kinesins reveals the diversity of kinesin-mediated transport., PMID:31461551
Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity., PMID:31084716
[Phenotypic and genotypic analysis of a girl carrying a 2q22.3 microduplication encompassing the MBD5 gene]., PMID:31055822
Human Epididymis Protein 4 Quantification and Interaction Network Analysis in Seminal Plasma., PMID:30919767
Adipocyte proteome and secretome influence inflammatory and hormone pathways in glioma., PMID:30302719
Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression., PMID:30174115
Investigating role of conformational changes of microtubule in regulating its binding affinity to kinesin by all-atom molecular dynamics simulation., PMID:30132979
Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons., PMID:30068641
Discovery and Validation of Methylation Biomarkers for Ulcerative Colitis Associated Neoplasia., PMID:29762666
Analysis of 17 genes detects mutations in 81% of 811 patients with lissencephaly., PMID:29671837
Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics., PMID:29588377
For research use only. Not for human or drug use.
