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Recombinant Human KPNA5 Protein, N-His

Catalog #:   YHA42701 Specific References (19) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: O15131
Protein length: Thr82-Gly503
Overview

Catalog No.

YHA42701

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Thr82-Gly503

Predicted molecular weight

49.12 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O15131

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Karyopherin subunit alpha-5, Importin subunit alpha-6, KPNA5

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human KPNA5 Protein
References

KPNA5 Suppresses Malignant Progression of Ovarian Cancer Through Importing the PTPN4 Into the Nucleus., PMID:40145330

Effect of Ivermectin and Atorvastatin on Nuclear Localization of Importin Alpha and Drug Target Expression Profiling in Host Cells from Nasopharyngeal Swabs of SARS-CoV-2- Positive Patients., PMID:34696514

Molecular profiling of nucleocytoplasmic transport factor genes in breast cancer., PMID:33553736

Regulation of the Ebola Virus VP24 Protein by SUMO., PMID:31597768

Ebolavirus interferon antagonists-protein interaction perspectives to combat pathogenesis., PMID:29140409

Investigating Ebola virus pathogenicity using molecular dynamics., PMID:28812539

Macrocyclic peptide inhibitors for the protein-protein interaction of Zaire Ebola virus protein 24 and karyopherin alpha 5., PMID:28574091

An all-atom molecular dynamics study of the anti-interferon signaling of Ebola virus: interaction mechanisms of EBOV VP24 binding to Karyopherin alpha5., PMID:28418440

VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability., PMID:27974555

Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses., PMID:27009368

In Silico Study of Plant Polyphenols' Interactions with VP24-Ebola Virus Membrane-associated Protein., PMID:26454589

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells., PMID:26255028

BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells., PMID:26052702

Global Characteristics of CSIG-Associated Gene Expression Changes in Human HEK293 Cells and the Implications for CSIG Regulating Cell Proliferation and Senescence., PMID:26029164

Cross-platform meta-analysis of multiple gene expression profiles identifies novel expression signatures in acquired anthracycline-resistant breast cancer., PMID:25695524

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1., PMID:25121748

How a virus blocks a cellular emergency access lane to the nucleus, STAT!, PMID:25121743

Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers., PMID:22302350

Physical map of the chromosome 6q22 region containing the oculodentodigital dysplasia locus: analysis of thirteen candidate genes and identification of novel ESTs and DNA polymorphisms., PMID:12584438

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Recombinant Human KPNA5 Protein, N-His [YHA42701]
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