Catalog No.
YHK50401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser148-His230
Predicted molecular weight
21.69 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9GZS0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DNAI2, Dynein intermediate chain 2, axonemal, Axonemal dynein intermediate chain 2
LRRC56 deletion causes primary ciliary dyskinesia in mice characterized by dynein arms defects., PMID:39912490
Exploring nasopharyngeal carcinoma genetics: Bioinformatics insights into pathways and gene associations., PMID:39352166
Association of novel DNAH11 variants with asthenoteratozoospermia lead to male infertility., PMID:39256880
Identification of high-risk non-synonymous SNPs (nsSNPs) in DNAH1 and DNAH17 genes associated with male infertility: a bioinformatics analysis., PMID:38874855
PTEN decreases NR2F1 expression to inhibit ciliogenesis during EGFRL858R-induced lung cancer progression., PMID:38499532
Naringenin attenuated airway cilia structural and functional injury induced by cigarette smoke extract via IL-17 and cAMP pathways., PMID:38359483
Experimental and molecular support for Cfap70 as a causative gene of 'multiple morphological abnormalities of the flagella' with male infertility†., PMID:37458246
Comparative transcriptome analysis identified crucial genes and pathways affecting sperm motility in the reproductive tract of drakes with different libido., PMID:36881978
Pathogenic variants in CLXN encoding the outer dynein arm docking-associated calcium-binding protein calaxin cause primary ciliary dyskinesia., PMID:36727596
Subtyping children with asthma by clustering analysis of mRNA expression data., PMID:36159986
PM2.5 Upregulates the Expression of MUC5AC via the EGFR-PI3K Pathway in Human Sinonasal Epithelial Cells., PMID:34736257
CCDC114, DNAI2 and TOP2A involves in the effects of tibolone treatment on postmenopausal endometrium., PMID:34116668
IFT46 Expression in the Nasal Mucosa of Primary Ciliary Dyskinesia Patients: Preliminary Study., PMID:33628615
Integrative bioinformatics approaches for identifying potential biomarkers and pathways involved in non-obstructive azoospermia., PMID:33532314
A novel genetic variant in DNAI2 detected by custom gene panel in a newborn with Primary Ciliary Dyskinesia: case report., PMID:33167880
DNA methylation-based diagnostic and prognostic biomarkers of nasopharyngeal carcinoma patients., PMID:32541515
Bioinformatic identification of candidate biomarkers and related transcription factors in nasopharyngeal carcinoma., PMID:30935420
Recessive DNAH9 Loss-of-Function Mutations Cause Laterality Defects and Subtle Respiratory Ciliary-Beating Defects., PMID:30471718
ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms., PMID:29601588
IL-13 regulates human nasal epithelial cell differentiation via H3K4me3 modification., PMID:29386911
Axonemal dynein assembly requires the R2TP complex component Pontin., PMID:29113992
The Role of the Notch Signal Pathway in Mucosal Cell Metaplasia in Mouse Acute Otitis Media., PMID:28676722
Alterations in oviductal cilia morphology and reduced expression of axonemal dynein in diabetic NOD mice., PMID:27823762
Role of IFN-γ, IL-13, and IL-17 on mucociliary differentiation of nasal epithelial cells in chronic rhinosinusitis with nasal polyps., PMID:26399381
HEATR2 plays a conserved role in assembly of the ciliary motile apparatus., PMID:25232951
Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm., PMID:24203976
Roflumilast inhibits respiratory syncytial virus infection in human differentiated bronchial epithelial cells., PMID:23936072
Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia., PMID:23261302
Respiratory syncytial virus inhibits ciliagenesis in differentiated normal human bronchial epithelial cells: effectiveness of N-acetylcysteine., PMID:23118923
Roflumilast N-oxide, a PDE4 inhibitor, improves cilia motility and ciliated human bronchial epithelial cells compromised by cigarette smoke in vitro., PMID:22385203
Characterization of the medaka (Oryzias latipes) primary ciliary dyskinesia mutant, jaodori: Redundant and distinct roles of dynein axonemal intermediate chain 2 (dnai2) in motile cilia., PMID:20709053
Dynein axonemal intermediate chain 2 is required for formation of the left-right body axis and kidney in medaka., PMID:20707998
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects., PMID:19944400
Ciliary defects and genetics of primary ciliary dyskinesia., PMID:19410201
DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm., PMID:18950741
Mouse dynein axonemal intermediate chain 2: cloning and expression., PMID:18547164
Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression., PMID:16809635
The human dynein intermediate chain 2 gene (DNAI2): cloning, mapping, expression pattern, and evaluation as a candidate for primary ciliary dyskinesia., PMID:11153919
The Bacillus subtilis dnaI gene is part of the dnaB operon., PMID:7773414
Functional analysis of the dna (Ts) mutants of Bacillus subtilis: plasmid pUB110 replication as a model system., PMID:3146018
For research use only. Not for human or drug use.
