Catalog No.
YHF39501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly188
Predicted molecular weight
23.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61019
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RAB2A, Ras-related protein Rab-2A, RAB2
ERK activation by Rab2B in the early secretory pathway impacts the ERGIC-Golgi interface., PMID:40037424
Involvement of GTPases and vesicle adapter proteins in Heparan sulfate biosynthesis: role of Rab1A, Rab2A and GOLPH3., PMID:39804811
Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification., PMID:39802509
Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes., PMID:39496977
ARL8B promotes hepatocellular carcinoma progression and inhibits antitumor activity of lenvatinib via MAPK/ERK signaling by interacting with RAB2A., PMID:39413890
Metastatic Leiomyoma With Malignant Transformation Harboring RAB2A-PLAG1 Fusion: A Case Report and Review With Molecular Analysis., PMID:39230504
Bottom-up approach to deciphering the targets of the ubiquitin-proteasome system in porcine sperm capacitation., PMID:39215164
Assessment of NB-UVB Effects on Skin of Atopic Dermatitis Patients: A Network Analysis., PMID:39188927
TBC1D4 antagonizes RAB2A-mediated autophagic and endocytic pathways., PMID:38964379
Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads., PMID:38935810
A dual role of ERGIC-localized Rabs in TMED10-mediated unconventional protein secretion., PMID:38926505
Unveiling the unexplored novel signatures for osteoporosis via a detailed bioinformatics and molecular experiments based approach., PMID:38715824
Controlled Plasma Membrane Delivery of FGFR1 and Modulation of Signaling by a Novel Regulated Anterograde RTK Transport Pathway., PMID:38136383
Integration of risk variants from GWAS with SARS-CoV-2 RNA interactome prioritizes FUBP1 and RAB2A as risk genes for COVID-19., PMID:37932299
The role of vesicle trafficking genes in osteoblast differentiation and function., PMID:37752218
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19., PMID:37198478
Hesperetin Ameliorates Inhibition of Neuronal and Oligodendroglial Cell Differentiation Phenotypes Induced by Knockdown of Rab2b, an Autism Spectrum Disorder-Associated Gene Product., PMID:36976668
Prediction of male fertility using Ras-related proteins., PMID:36812003
Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes., PMID:36640308
Genome-wide association study of the response of patients with diabetic macular edema to intravitreal Anti-VEGF injection., PMID:36581632
Novel Causal Plasma Proteins for Hypothyroidism: A Large-scale Plasma Proteome Mendelian Randomization Analysis., PMID:36190832
ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19., PMID:35970849
RAB2A promotes cervical cancer progression as revealed by comprehensive analysis of HPV integration and proteome in longitudinal cervical samples., PMID:35343109
High Resolution Proteomic Analysis of Subcellular Fractionated Boar Spermatozoa Provides Comprehensive Insights Into Perinuclear Theca-Residing Proteins., PMID:35252197
Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARγ., PMID:35061665
FAM71F1 binds to RAB2A and RAB2B and is essential for acrosome formation and male fertility in mice., PMID:34714330
LncRNA SOX2-OT regulates miR-192-5p/RAB2A axis and ERK pathway to promote glioblastoma cell growth., PMID:34470582
Identification and characterization of hADSC-derived exosome proteins from different isolation methods., PMID:34235869
MiR-381-3p/RAB2A axis activates cell proliferation and inhibits cell apoptosis in bladder cancer., PMID:33040796
miR-376c-3p modulates the properties of breast cancer stem cells by targeting RAB2A., PMID:32963598
New insights regarding SNARE proteins in autophagosome-lysosome fusion., PMID:32924745
Comprehensive analysis of the value of RAB family genes in prognosis of breast invasive carcinoma., PMID:32432324
Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the Brucella Intracellular Cycle., PMID:32234817
New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD., PMID:31286804
RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells., PMID:30957628
Identification of a novel BOC-PLAG1 fusion gene in a case of lipoblastoma., PMID:30857637
MicroRNA‑192 acts as a tumor suppressor in colon cancer and simvastatin activates miR‑192 to inhibit cancer cell growth., PMID:30628692
Xiao-Xu-Ming decoction extract regulates differentially expressed proteins in the hippocampus after chronic cerebral hypoperfusion., PMID:30539815
Quantitative proteomic profiling indicates the difference in reproductive efficiency between Meishan and Duroc boar spermatozoa., PMID:29778923
SGSM2, a putative Rab2a GAP, regulates lysozyme sorting in Paneth cells., PMID:29527623
Identification of UT-A1- and AQP2-interacting proteins in rat inner medullary collecting duct., PMID:29046292
Rab2 promotes autophagic and endocytic lysosomal degradation., PMID:28483915
Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells., PMID:28330897
Harnessing membrane trafficking to promote cancer spreading and invasion: The case of RAB2A., PMID:28060560
Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2., PMID:27927751
The impact of erdosteine on cisplatin-induced ototoxicity: a proteomics approach., PMID:27878588
S100A7 has an oncogenic role in oral squamous cell carcinoma by activating p38/MAPK and RAB2A signaling pathway., PMID:27767088
TBC1D20 mediates autophagy as a key regulator of autophagosome maturation., PMID:27487390
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs., PMID:27255086
De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia., PMID:26938441
For research use only. Not for human or drug use.
