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Recombinant Human RHOT2 Protein, N-His

Catalog #:   YHK43201 Specific References (46) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q8IXI1
Protein length: Glu177-Phe589
Overview

Catalog No.

YHK43201

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Glu177-Phe589

Predicted molecular weight

47.78 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q8IXI1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Ras homolog gene family member T2, MIRO-2, ARHT2, hMiro-2, Mitochondrial Rho GTPase 2, C16orf39, RHOT2

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human RHOT2 Protein
References

Identification of susceptibility modules and characteristic genes to osteoarthritis by WGCNA., PMID:39297544

Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes., PMID:37158593

Investigation of putative roles of smoking-associated salivary microbiome alterations on carcinogenesis by integrative in silico analysis., PMID:36587566

Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits., PMID:35941285

MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control., PMID:34873283

Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response., PMID:34152608

Coordination of mitochondrial and cellular dynamics by the actin-based motor Myo19., PMID:34013964

Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase., PMID:33132189

Age-Dependent Assessment of Genes Involved in Cellular Senescence, Telomere, and Mitochondrial Pathways in Human Lung Tissue of Smokers, COPD, and IPF: Associations With SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 Axis., PMID:33013423

The role of RHOT1 and RHOT2 genetic variation on Parkinson disease risk and onset., PMID:32948353

Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis., PMID:32702724

Age-dependent assessment of genes involved in cellular senescence, telomere and mitochondrial pathways in human lung tissue of smokers, COPD and IPF: Associations with SARS-CoV-2 COVID-19 ACE2-TMPRSS2-Furin-DPP4 axis., PMID:32587985

Peroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2., PMID:31894645

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery., PMID:31562315

Miro2 Regulates Inter-Mitochondrial Communication in the Heart and Protects Against TAC-Induced Cardiac Dysfunction., PMID:31455181

Preserving Mitochondrial Structure and Motility Promotes Recovery of White Matter After Ischemia., PMID:31152363

Myc Regulation of a Mitochondrial Trafficking Network Mediates Tumor Cell Invasion and Metastasis., PMID:31061095

Miro-dependent mitochondrial pool of CENP-F and its farnesylated C-terminal domain are dispensable for normal development in mice., PMID:30856164

Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy., PMID:30806158

Epigenetic signature: implications for mitochondrial quality control in human aging., PMID:30787202

Miro proteins prime mitochondria for Parkin translocation and mitophagy., PMID:30504269

Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism., PMID:30513825

GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells., PMID:30459446

Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX., PMID:30111583

Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases., PMID:29943371

Genomic convergence of locus-based GWAS meta-analysis identifies AXIN1 as a novel Parkinson's gene., PMID:29923028

NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels., PMID:29891729

Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution., PMID:29311115

A PGAM5-KEAP1-Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking., PMID:28839075

TNFα decreases mitochondrial movement in human airway smooth muscle., PMID:28473328

A neuronal network of mitochondrial dynamics regulates metastasis., PMID:27991488

Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites., PMID:27705781

Structural insights into Parkin substrate lysine targeting from minimal Miro substrates., PMID:27605430

Characterization of the three zebrafish orthologs of the mitochondrial GTPase Miro/Rhot., PMID:26482085

Mitotic redistribution of the mitochondrial network by Miro and Cenp-F., PMID:26259702

Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice., PMID:25680233

Mitochondrial trafficking in neurons and the role of the Miro family of GTPase proteins., PMID:24256248

The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2., PMID:22569362

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility., PMID:22078885

Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex., PMID:20335458

HUMMR, a hypoxia- and HIF-1alpha-inducible protein, alters mitochondrial distribution and transport., PMID:19528298

Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking., PMID:19152501

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase., PMID:19098100

The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking., PMID:16630562

Cloning and characterization of the mouse Arht2 gene which encodes a putative atypical GTPase., PMID:15218247

Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis., PMID:12482879

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human RHOT2 Protein, N-His [YHK43201]
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