Catalog No.
YHK38301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu43-Val153
Predicted molecular weight
25.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6NZI2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Polymerase I and transcript release factor, CAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF
Proteomics of colorectal tumors identifies the role of CAVIN1 in tumor relapse., PMID:40269326
Nanobodies against Cavin1 reveal structural flexibility and regulated interactions of its N-terminal coiled-coil domain., PMID:40260863
Alterations in RNA Expression Profile Following S. aureus and S. epidermidis Inoculation into Platelet Concentrates., PMID:40243635
Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis., PMID:39988583
HHIP protein interactions in lung cells provide insight into COPD pathogenesis., PMID:39945347
CAVIN-2 positively correlates with diabetic PAD and promotes LDL transcytosis by inhibiting eNOS activation., PMID:39887709
Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle disease., PMID:39819455
Hypoosmotic stress shifts transcription of circadian genes., PMID:39754358
Comprehensive analysis of the prognostic and immunological role of cavins in non-small cell lung cancer., PMID:39695458
The spectrum of rippling muscle disease., PMID:39370631
Regulation of cancer cell ferroptosis by PTRF/Cavin-1., PMID:39079051
Predictive and Experimental Motif Interaction Analysis Identifies Functions of the WNK-OSR1/SPAK Pathway., PMID:38979344
Upregulation of caveolae-associated structural proteins in the hair follicle bulge of lichen planopilaris and frontal fibrosing alopecia., PMID:38837051
CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT., PMID:38682330
HHIP protein interactions in lung cells provide insight into COPD pathogenesis., PMID:38617310
Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane., PMID:38517935
Downregulation of Caveolae-Associated Proteins in Psoriasis: A Case Series Study., PMID:38445230
Metabolic and other morbid complications in congenital generalized lipodystrophy type 4., PMID:38234231
The Cavin-1/Caveolin-1 interaction attenuates BMP/Smad signaling in pulmonary hypertension by interfering with BMPR2/Caveolin-1 binding., PMID:38182755
Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma., PMID:38092144
CD_99 G1 neutrophils modulate osteogenic differentiation of mesenchymal stem cells in the pathological process of ankylosing spondylitis., PMID:37977819
Role of Caveolae family-related proteins in the development of breast cancer., PMID:37828916
Fallopian tube lesions as potential precursors of early ovarian cancer: a comprehensive proteomic analysis., PMID:37775701
Cavin1 activates the Wnt/β-catenin pathway to influence the proliferation and migration of hepatocellular carcinoma., PMID:37774837
Upregulation of Caveolae-Associated Proteins in Lesional Samples of Hidradenitis Suppurativa: A Case Series Study., PMID:37731470
Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience., PMID:37672337
EPIC-1042 as a potent PTRF/Cavin1-caveolin-1 interaction inhibitor to induce PARP1 autophagic degradation and suppress temozolomide efflux for glioblastoma., PMID:37651725
A new mutation in the CAVIN1/PTRF gene in two siblings with congenital generalized lipodystrophy type 4: case reports and review of the literature., PMID:37501786
CAVIN2/SDPR Functioned as a Tumor Suppressor in Lung Adenocarcinoma from Systematic Analysis of Caveolae-Related Genes and Experimental Validation., PMID:37497407
PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation., PMID:37454215
Caveolin-1 in Müller Glia Exists as Heat-Resistant, High Molecular Weight Complexes., PMID:37440041
Molecular and clinical characterization of PTRF in glioma via 1,022 samples., PMID:37322408
Caveolae and the oxidative stress response., PMID:37248872
The intertwining roles of caveolin, oxytocin receptor, and the associated signalling pathways in prostate cancer progression., PMID:37217187
Diterpenoid Tanshinone Attenuates the Metastasis of Non-small-cell Lung Cancer (NSCLC) Cells by Inhibiting the Cavin-1-mediated ERK/Smad2 Signaling Pathway., PMID:37066773
The Potential of Lipid Droplet-associated Genes as Diagnostic and Prognostic Biomarkers in Head and Neck Squamous Cell Carcinoma., PMID:36998140
Serum amyloid A and interleukin -1β facilitate LDL transcytosis across endothelial cells and atherosclerosis via NF-κB/caveolin-1/cavin-1 pathway., PMID:36935311
Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2., PMID:36858041
A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome., PMID:36776558
Defected lipid rafts suppress cavin1-dependent IFN-α signaling endosome in paroxysmal nocturnal hemoglobinuria., PMID:36608443
Immune-Mediated Rippling Muscle Disease Associated With Thymoma and Anti-MURC/Cavin-4 Autoantibodies., PMID:36522170
A Novel High-Throughput Screening Method for a Human Multicentric Osteosarcoma-Specific Antibody and Biomarker Using a Phage Display-Derived Monoclonal Antibody., PMID:36497311
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1., PMID:36443833
Gene and Protein Accumulation Changes Evoked in Porcine Aorta in Response to Feeding with Two Various Fructan Sources., PMID:36428375
Preliminary Extracellular Vesicle Profiling in Drainage Fluid After Neck Dissection in OSCC., PMID:36331313
Testosterone improved erectile function by upregulating transcriptional expression of growth factors in late androgen replacement therapy model rats., PMID:36310186
Proteomics and liquid biopsy characterization of human EMT-related metastasis in colorectal cancer., PMID:36249004
DHCR24 Knockdown Induces Tau Hyperphosphorylation at Thr181, Ser199, Ser262, and Ser396 Sites via Activation of the Lipid Raft-Dependent Ras/MEK/ERK Signaling Pathway in C8D1A Astrocytes., PMID:35804281
Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease., PMID:35729002
Expression of the Cavin Family in Childhood Leukemia and Its Implications in Subtype Diagnosis and Prognosis Evaluation., PMID:35722492
For research use only. Not for human or drug use.
