Research Grade Anti-Human CD120a/TNFRSF1A/TNFR1 (GSK1995057)

Catalog No.

DHD34003

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

dAb (VHH-His)

Clonality

Monoclonal

Target

TNFR-I, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor superfamily member 1A, TBPI, p60, CD120a, TNFRSF1A, Tumor necrosis factor receptor type I, p55, TNF-RI, TNFAR, TNFR1, TNF-R1

Concentration

1.63 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19438

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

PBS pH 7.4, 0.2M Arg

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

GSK1995057

Clone ID

GSK1995057

Immunogenicity and humanization of single-domain antibodies., PMID:33751827

Inhibition of TNFR1 Attenuates LPS Induced Apoptosis and Inflammation in Human Nucleus Pulposus Cells by Regulating the NF-KB and MAPK Signalling Pathway., PMID:33713325

Detection of Memory B Activity Against a Therapeutic Protein in Treatment-Naïve Subjects., PMID:29549534

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury., PMID:29382797

Specificity of human anti-variable heavy (VH ) chain autoantibodies and impact on the design and clinical testing of a VH domain antibody antagonist of tumour necrosis factor-α receptor 1., PMID:26178412

Autoantibodies to variable heavy (VH) chain Ig sequences in humans impact the safety and clinical pharmacology of a VH domain antibody antagonist of TNF-α receptor 1., PMID:23832582

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Research Grade Anti-Human CD120a/TNFRSF1A/TNFR1 (GSK1995057).pdf