Research Grade Anti-Human SLC44A4 (ASG-5ME)

Catalog No.

DHH88401

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

SLC44A4, Choline transporter-like protein 4, CTL4, NG22, Thiamine pyrophosphate transporter 1, Solute carrier family 44 member 4, TPPT1, C6orf29, hTPPT1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q53GD3

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

ASG-5ME, ASG 5ME, ASG5ME

Clone ID

ASG-5ME

A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4-targeting antibody carrying auristatin E, in metastatic castration-resistant prostate cancer., PMID:30725389

The Discovery and Preclinical Development of ASG-5ME, an Antibody-Drug Conjugate Targeting SLC44A4-Positive Epithelial Tumors Including Pancreatic and Prostate Cancer., PMID:27550944

A phase 1 clinical trial of ASG-5ME, a novel drug-antibody conjugate targeting SLC44A4, in patients with advanced pancreatic and gastric cancers., PMID:26994014

Discontinued in 2013: oncology drugs., PMID:25315907

Novel agents in the treatment of pancreatic adenocarcinoma., PMID:23474556

IBC's 21st Annual Antibody Engineering and 8th Annual Antibody Therapeutics International Conferences and 2010 Annual Meeting of the Antibody Society. December 5-9, 2010, San Diego, CA USA., PMID:21304271

Document Download

Research Grade Anti-Human SLC44A4 (ASG-5ME).pdf