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Anti-Human Big Endothelin1/Big-ET-1 Antibody (SAA0803)

Catalog #:   RHC15901 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA
Accession: P05305
Overview

Catalog No.

RHC15901

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Target

Endothelin-1, EDN1, PPET1, ET-1, Preproendothelin-1,Endothelin1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05305

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0803

Data Image
References

Effect of domperidone (leisguard®) on antibody titers, inflammatory markers and creatinine in dogs with leishmaniosis and chronic kidney disease., PMID:34629081

Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension., PMID:30636542

New drugs and emerging therapeutic targets in the endothelin signaling pathway and prospects for personalized precision medicine., PMID:29947527

Endothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptor., PMID:24901342

Cathepsin E induces itch-related response through the production of endothelin-1 in mice., PMID:22546226

Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta., PMID:19541930

Estrogen replacement increases matrix metalloproteinase contribution to vasoconstriction in a rat model of menopause., PMID:19412129

Endothelin-1 in humans is increased by oxygen-derived radicals ex vivo and in vivo., PMID:17963680

Localization of the endothelin system in human diffuse astrocytomas., PMID:16007684

Dual effects of endothelin-1 (1-31): induction of mesangial cell migration and facilitation of monocyte recruitment through monocyte chemoattractant protein-1 production by mesangial cells., PMID:15253109

Comparison between the surface plasmon resonance (SPR) and the quartz crystal microbalance (QCM) method in a structural analysis of human endothelin-1., PMID:15142610

Cellular distribution of the endothelin system in the human brain., PMID:15121213

Comparative sequences of canine and feline endothelin-1., PMID:14655103

An immunohistochemical study of endothelin-1 converting enzyme in the human eye., PMID:12187489

Biochemical characterization of endothelin-converting enzyme-1alpha in cultured skin-derived cells and its postulated role in the stimulation of melanogenesis in human epidermis., PMID:11723113

Endothelin-1 pathway in human alveolar epithelial cell line A549 and human umbilical vein endothelial cells., PMID:11360683

Plasma endothelin is increased in early essential hypertension., PMID:10912738

Synthesis and receptor sites of endothelin-1 in the rat liver vasculature., PMID:10903535

Immunohistochemical distribution of the endothelin-converting enzyme-1 in the rat hypothalamo-pituitary axis., PMID:10771167

Critical factors in the radioimmunoassay of endothelin-1, endothelin-3, and big endothelin-1 in human plasma., PMID:10660455

Sequencing, expression and biochemical characterization of the Porphyromonas gingivalis pepO gene encoding a protein homologous to human endothelin-converting enzyme., PMID:10571076

Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor., PMID:10559137

Endothelin converting enzyme is located on alpha-actin filaments in smooth muscle cells., PMID:10533622

Immunohistochemical localization of endothelin-1/big endothelin-1 in normal liver, liver cirrhosis and hepatocellular carcinoma., PMID:10091381

Monoclonal antibodies against human endothelin-converting enzyme-1., PMID:9682125

Regulation of endothelin-1 in human non-pigmented ciliary epithelial cells by tumor necrosis factor-alpha., PMID:9533826

Detection and epitope mapping of immunoreactive human endothelin-1 using ELISA and a surface plasmon resonance-based biosensor., PMID:9421886

Sandwich-type enzyme immunoassay for big endothelin-I in plasma: concentrations in healthy human subjects unaffected by sex or posture., PMID:8990224

Endothelin-1 and big endothelin-1 increase in human endometrium during menstruation., PMID:7503189

Localization of rat endothelin-converting enzyme to vascular endothelial cells and some secretory cells., PMID:7487910

Effect of volume support, antibiotic therapy, and monoclonal antiendotoxin antibodies on mortality rate and blood concentrations of endothelin and other mediators in fulminant intra-abdominal sepsis in rats., PMID:7634809

A rapid and versatile method for screening endothelin converting enzyme activity., PMID:7949376

Endothelin-1 secretion by human gallbladder epithelial cells in primary culture., PMID:8264237

Production and characterization of monoclonal antibodies to the carboxyl-terminal heptapeptide of endothelin-1., PMID:8244418

Enzyme immunometric assay for endothelin using tandem monoclonal antibodies., PMID:7686198

Localization of endothelin-1-like immunoreactivity in human placenta., PMID:8450193

Determination of endothelin by an immobilized receptor assay utilizing a 96-well format., PMID:1491102

Radioimmunoassay of endothelin in human plasma., PMID:1345052

Concentrations and ratios of immunoreactive big-endothelin-1 and endothelin-1 in human, rat and rabbit plasma., PMID:1417908

Regional differences in endothelin converting enzyme activity in rat brain: inhibition by phosphoramidon and EDTA., PMID:1393292

Monoclonal antibodies to human endothelin-1: characterization and utilization in radioimmunoassay and immunocytochemistry., PMID:1607212

A rabbit antiserum raised against the hexapeptide endothelin(16-21) shows different binding affinities for endothelin-1, -2 and -3., PMID:1593928

Radio-immunoassay of endothelin in human plasma., PMID:1810021

Endothelin-1 and endothelin-3 play different roles in acute and chronic alterations of blood pressure in patients with chronic hemodialysis., PMID:2069568

Demonstration and nature of endothelin-3-like immunoreactivity in somatostatin and choline acetyltransferase-immunoreactive nerve cells of the neostriatum of the rat., PMID:1676496

Development and application of three radioimmunoassays of endothelin of varying specificities., PMID:1725400

Sandwich-enzyme immunoassays for endothelin family peptides., PMID:1725398

[Validation of radioimmunoassay of tissue and plasma endothelin-1]., PMID:2124465

Endothelin-3 concentrations in human plasma: the increased concentrations in patients undergoing haemodialysis., PMID:2192712

Purification and characterization of putative endothelin converting enzyme in bovine adrenal medulla: evidence for a cathepsin D-like enzyme., PMID:2189405

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human Big Endothelin1/Big-ET-1 Antibody (SAA0803) [RHC15901]
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