Research Grade Anti-Human CD340/ERBB2/HER2/NEU (HuA21)

Catalog No.

DHC09626

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG

Clonality

Monoclonal

Target

p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04626

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

HuA21

Clone ID

HuA21

A novel 4-1BB/HER2 bispecific antibody shows potent antitumor activities by increasing and activating tumor-infiltrating T cells., PMID:37559991

Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells., PMID:31205018

Development and Characterization of a Humanized Anti-HER2 Antibody HuA21 with Potent Anti-Tumor Properties in Breast Cancer Cells., PMID:27092488

Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing Technologies., PMID:26046845

PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability., PMID:12913148

HEN1 functions pleiotropically in Arabidopsis development and acts in C function in the flower., PMID:11874905

HUA1, a regulator of stamen and carpel identities in Arabidopsis, codes for a nuclear RNA binding protein., PMID:11595801

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Research Grade Anti-Human CD340/ERBB2/HER2/NEU (HuA21).pdf