Catalog No.
FHD04810
Species reactivity
Human
Host species
Human
Isotype
VHH-hFc
Clonality
Monoclonal
Conjugation
Unconjugated
Target
D(2) dopamine receptor, Dopamine D2 receptor, DRD2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P14416
Applications
Blocking, ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0772
Valproic acid promotes transcriptional activation of Drd2 by mediating histone acetylation to inhibit the mTOR-Pttg1 signaling axis and exerts anti-PitNETs activity., PMID:40220407
The First Pilot Epigenetic Type Improvement of Neuropsychiatric Symptoms in a Polymorphic Dopamine D2 (-DRD2/ANKK (Taq1A)), OPRM1 (A/G), DRD3 (C/T), and MAOA (4R) Compromised Preadolescence Male with Putative PANDAS/CANS: Positive Clinical Outcome with Precision-Guided DNA Testing and Pro-Dopamine Regulation (KB220) and Antibacterial Therapies., PMID:39507617
Anti-dopamine receptor 2 antibody encephalitis in adults: a case report., PMID:39425067
Dopamine receptor autoantibody signaling in infectious sequelae differentiates movement versus neuropsychiatric disorders., PMID:39325550
Hypothesizing That Pediatric Autoimmune Neuropsychiatric Associated Streptococcal (PANDAS) Causes Rapid Onset of Reward Deficiency Syndrome (RDS) Behaviors and May Require Induction of "Dopamine Homeostasis"., PMID:36407790
Sex differences in saliva-based DNA methylation changes and environmental stressor in young African American adults., PMID:36067197
Effects of Cyclosporine A and Adalimumab on the expression profiles histaminergic system-associated genes and microRNAs regulating these genes in HaCaT cells., PMID:35899934
HERV-W Envelope Triggers Abnormal Dopaminergic Neuron Process through DRD2/PP2A/AKT1/GSK3 for Schizophrenia Risk., PMID:35062349
Subcellular localization of D2 receptors in the murine substantia nigra., PMID:34854963
Tumor suppressor DRD2 facilitates M1 macrophages and restricts NF-κB signaling to trigger pyroptosis in breast cancer., PMID:33859743
Dystonia: Sparse Synapses for D2 Receptors in Striatum of a DYT1 Knock-out Mouse Model., PMID:32041188
Bovine dopamine type-2 receptor SNP has no effect on growth, semen characteristics and prolactin concentrations in beef bulls treated with a dopamine agonist., PMID:31208851
[Pituitary lactotroph adenomas resistant to dopamine agonist treatment: histological and immunohistochemical characteristics]., PMID:29927438
Study of Novel Autoantibodies in Schizophrenia., PMID:29373732
Anti-neuronal anti-bodies in patients with early psychosis., PMID:28461116
Induction of dopamine D1 and D5 receptors in R28 cells by light exposures., PMID:28336436
Validation of dopamine receptor DRD1 and DRD2 antibodies using receptor deficient mice., PMID:28316027
Dopamine-2 receptor extracellular N-terminus regulates receptor surface availability and is the target of human pathogenic antibodies from children with movement and psychiatric disorders., PMID:27908295
Response of colonic motility to dopaminergic stimulation is subverted in rats with nigrostriatal lesion: relevance to gastrointestinal dysfunctions in Parkinson's disease., PMID:26433214
Trace amine-associated receptor 1 activation silences GSK3β signaling of TAAR1 and D2R heteromers., PMID:26372541
Evidence of D2 receptor expression in the nucleus incertus of the rat., PMID:26300469
Social interaction reward decreases p38 activation in the nucleus accumbens shell of rats., PMID:26300300
Pancreatic Endocrine Effects of Dopamine Receptors in Human Islet Cells., PMID:25931261
Evidence for limited D1 and D2 receptor coexpression and colocalization within the dorsal striatum of the neonatal mouse., PMID:25556545
Reacquisition of cocaine conditioned place preference and its inhibition by previous social interaction preferentially affect D1-medium spiny neurons in the accumbens corridor., PMID:25309368
Antibodies to surface dopamine-2 receptor and N-methyl-D-aspartate receptor in the first episode of acute psychosis in children., PMID:25168608
The expression profile of Dopamine D2 receptor, MGMT and VEGF in different histological subtypes of pituitary adenomas: a study of 197 cases and indications for the medical therapy., PMID:25027022
Beta-amyloid auto-antibodies are reduced in Alzheimer's disease., PMID:25022335
δ-opioid and dopaminergic processes in accumbens shell modulate the cholinergic control of predictive learning and choice., PMID:24453326
Brain human monoclonal autoantibody from sydenham chorea targets dopaminergic neurons in transgenic mice and signals dopamine D2 receptor: implications in human disease., PMID:24184556
In vitro expressed GPCR inserted in polymersome membranes for ligand-binding studies., PMID:23161746
Characterization of dopamine D1 and D2 receptor-expressing neurons in the mouse hippocampus., PMID:22777829
Combinatorial topography and cell-type specific regulation of the ERK pathway by dopaminergic agonists in the mouse striatum., PMID:22453353
Retinoic acid-dependent and -independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons., PMID:22069189
Evidences for the existence of a low dopaminergic tone in polycystic ovarian syndrome: implications for OHSS development and treatment., PMID:21646367
Inhibitory effects of antivascular endothelial growth factor strategies in experimental dopamine-resistant prolactinomas., PMID:21406548
The ANKK1 gene associated with addictions is expressed in astroglial cells and upregulated by apomorphine., PMID:19853839
L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice., PMID:19187092
Differential repression by freud-1/CC2D1A at a polymorphic site in the dopamine-D2 receptor gene., PMID:17535813
Autoantibodies against four kinds of neurotransmitter receptors in psychiatric disorders., PMID:12965267
Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome., PMID:12851722
For research use only. Not for human or drug use.
