Catalog No.
FHD75210
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Calreticulin, ERp60, CRTC, Calregulin, grp60, HACBP, Endoplasmic reticulum resident protein 60, CALR, CRP55
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27797
Applications
FCM, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0511
Generation of a Synthetic Single Domain Antibody Library for Radiopharmaceutical Ligand Discovery., PMID:40463173
Patritumab deruxtecan induces immunogenic cell death., PMID:40458967
Defective neutrophil clearance in JAK2V617F myeloproliferative neoplasms drives myelofibrosis via immune checkpoint CD24., PMID:40373279
The anti-FRα antibody-drug conjugate luveltamab tazevibulin demonstrates efficacy in non-small cell lung cancer preclinical models and induces immunogenic cell death., PMID:40293943
Synergistic Induction of Immunogenic Cell Death by Biomineralized Manganese and Bisphosphonates Enhances Anti-PD-L1 Therapy in Triple-Negative Breast Cancer., PMID:40276640
LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth., PMID:40217513
PD-L1 targeted antibody-polymer-Epirubicin conjugate prolongs survival in a preclinical murine model of advanced ovarian cancer., PMID:40185333
Dual blockade of GSTK1 and CD47 improves macrophage-mediated phagocytosis on cancer cells., PMID:40147800
CALR-mutated myeloproliferative neoplasms., PMID:39960832
[Immunohistochemical method of megakaryocytic lineage staining in bone marrow biopsy specimens as an additional pathomorphological differential diagnostic sign of primary myelofibrosis and essential thrombocythemia]., PMID:39943725
Mutant Calreticulin in MPN: Mechanistic Insights and Therapeutic Implications., PMID:39775969
Anaplastic Lymphoma Kinase (ALK) Inhibitors Enhance Phagocytosis Induced by CD47 Blockade in Sensitive and Resistant ALK-Driven Malignancies., PMID:39767726
A non-invasive model for diagnosis of primary Sjogren's disease based on salivary biomarkers, serum autoantibodies, and Schirmer's test., PMID:39695856
Novel approaches in myelofibrosis., PMID:39670187
FVIIa-PAR2 signaling facilitates immune escape by reducing phagocytic potential of macrophages in breast cancer., PMID:39667690
INCA033989: the first shot on goal for MPNs?, PMID:39607716
Discovery of an theranostic functional mAb for visualizing the sensitivity and effectiveness of PD-L1 checkpoint therapy., PMID:39603072
CD47 and Calreticulin Expression in Breast Cancer Subtypes and Anti-CD47 Inhibitory Effects in Macrophage-mediated Phagocytosis., PMID:39477308
Epigallocatechin-3-gallate induces immunogenic cell death and enhances cancer immunotherapy in colorectal cancer., PMID:39471680
New approaches to standard of care in early-phase myeloproliferative neoplasms: can interferon-α alter the natural history of the disease?, PMID:39445431
Dendritic Cells Loaded With Heat Shock Inactivated Glioma Stem Cells Enhance Antitumor Response of Mouse Glioma When Combining With CD47 Blockade., PMID:39429684
Reprogramming tumor microenvironment with precise photothermal therapy by calreticulin nanobody-engineered probiotics., PMID:39303415
Photodynamic Therapy Using RGD-Functionalized Quantum Dots Elicit a Potent Immune Response in a Syngeneic Mouse Model of Pancreatic Cancer., PMID:39290860
Synthesis and immunotherapy efficacy of a PD-L1 small-molecule inhibitor combined with its 131I-iodide labelled isostructural compound., PMID:39276489
Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN., PMID:39255409
A Case of Autoimmune Myelofibrosis Associated With Autoimmune Hepatitis., PMID:39247061
The CALR mutations enhance the expression of the immunosuppressive proteins GARP and LAP on peripheral blood lymphocytes through increased binding of activated platelets., PMID:39161981
Blockade of glucose-6-phosphate dehydrogenase induces immunogenic cell death and accelerates immunotherapy., PMID:39089738
Sequential Double Immunoblotting with Peptide Antibodies., PMID:38997494
Synergistic action of gemcitabine and celecoxib in promoting the antitumor efficacy of anti-programmed death-1 monoclonal antibody by triggering immunogenic cell death., PMID:38988937
Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response., PMID:38950333
Detection of anti-calreticulin antibody in the sera of Chinese patients with primary Sjögren syndrome., PMID:38896912
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment., PMID:38885318
Branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status to boost anti-PD-L1 antibody therapy., PMID:38799622
Dual role of the peptide-loading complex as proofreader and limiter of MHC-I presentation., PMID:38771881
Characterization of antigenic proteins of the Taenia solium postoncospheral form., PMID:38705360
Crystal structure of Trichinella spiralis calreticulin and the structural basis of its complement evasion mechanism involving C1q., PMID:38690267
Codelivery of anti-CD47 antibody and chlorin e6 using a dual pH-sensitive nanodrug for photodynamic immunotherapy of osteosarcoma., PMID:38560565
CD40 stimulation via CD40 ligand enhances adenovirus-mediated tumour immunogenicity including 'find-me', 'eat-me', and 'kill-me' signalling., PMID:38494863
Optical biosensor based on weak measurement for ultra-sensitive detection of calreticulin in human serum., PMID:38404297
The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy., PMID:38323311
Targeting TACC3 Induces Immunogenic Cell Death and Enhances T-DM1 Response in HER2-Positive Breast Cancer., PMID:38319231
Opaganib (ABC294640) Induces Immunogenic Tumor Cell Death and Enhances Checkpoint Antibody Therapy., PMID:38069222
Therapeutic Efficacy of Oxaliplatin and Pembrolizumab Combination Treatment for Triple-Negative Breast Cancer., PMID:38007758
Quantitative image analysis of intracellular protein translocation in 3-dimensional tissues for pharmacodynamic studies of immunogenic cell death., PMID:37981052
AMPK activation induces immunogenic cell death in AML., PMID:37903311
Hollow Cu2MoS4 nanoparticles loaded with immune checkpoint inhibitors reshape the tumor microenvironment to enhance immunotherapy for pancreatic cancer., PMID:37890815
A single photodynamic priming protocol augments delivery of ⍺-PD-L1 mAbs and induces immunogenic cell death in head and neck tumors., PMID:37818742
Recent advances in therapies for primary myelofibrosis., PMID:37771602
Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer., PMID:37745348
For research use only. Not for human or drug use.
