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Anti-Mouse C5a Antibody (SAA0496)

Catalog #:   RMB90001 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: ELISA, SPR, WB
Accession: P06684
Overview

Catalog No.

RMB90001

Species reactivity

Mouse

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Complement C5, Hemolytic complement, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P06684

Applications

ELISA, SPR, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA0496

Data Image
References

Is COVID-19 Coagulopathy a Thrombotic Microangiopathy? A Prospective, Observational Study., PMID:40508203

Advances in the treatment of ANCA-associated vasculitis., PMID:40473820

Recombinant C5a Peptidase and Formalin-Killed Cell: A Synergistic Vaccine Against Streptococcus iniae in Four-Finger Threadfin Fish (Eleutheronema tetradactylum)., PMID:40420522

The molecular adjuvant effect of the C-terminal peptide of complement C5a in a teleost fish., PMID:40373887

Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis., PMID:40370446

Correlations of the Complement Proteins MASP-2 and MASP-3 With Clinical Severity and Short-Term Outcomes in Primary Membranous Nephropathy Patients., PMID:40294883

A selective C5a-derived peptidomimetic enhances IgG response following inactivated SARS-CoV-2 immunization and confers rapid disease resolution following murine coronavirus infection., PMID:40255397

Regional comparison of efficacy and safety for vilobelimab in critically ill, invasively mechanically ventilated COVID-19 patients., PMID:40250846

Complement C3 Deficiency Enhances Renal Leptospiral Load and Inflammation While Impairing T Cell Differentiation During Chronic Leptospira interrogans Infection., PMID:40236016

An antibody-dependent cellular phagocytosis-related gene signature predicts survival and response to immunotherapy in stomach adenocarcinoma., PMID:40193680

Safety of Avacopan for the Treatment of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: Combined Data From Three Clinical Trials., PMID:40192160

Emerging targeted therapies in ANCA-associated vasculitis., PMID:40071424

Highlights from the breakout session: optimising new treatments., PMID:40071420

Decreased concentrations of C5a complement receptor antibodies are associated with relapse in eosinophilic granulomatosis with polyangiitis (EGPA)., PMID:40050040

CD21lo B cell subsets are recruited to the central nervous system in acute neuromyelitis optica., PMID:40042820

Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis., PMID:40010959

Ravulizumab and other complement inhibitors for the treatment of autoimmune disorders., PMID:39983521

The Expanding Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Armamentarium., PMID:39969779

Efficacy and safety of avacopan in antineutrophil cytoplasmic autoantibody-associated vasculitis: a retrospective cohort study in Japan., PMID:39844309

Autoantibodies cause nociceptive sensitization in a mouse model of degenerative osteoarthritis., PMID:39835597

Evaluating Avacopan in the Treatment of ANCA-Associated Vasculitis: Design, Development and Positioning of Therapy., PMID:39803605

AChR-blocking antibodies and complement system dynamics: evaluating their interplay and clinical implications in myasthenia gravis., PMID:39676116

Expression of FcμR by bovine mononuclear blood leukocytes., PMID:39674305

Avacopan as an add-on therapy for ANCA-associated vasculitis: a pharmacological overview., PMID:39611585

Role of Avacopan on Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis., PMID:39597819

The Clinical and Molecular Response of Pyoderma Gangrenosum to IL-23 Blockade: Result from a Proof-of-Concept Open-Label Clinical Trial., PMID:39547392

An evaluation of vilobelimab (anti-C5a) as a cost-effective option to treat severely ill mechanically ventilated patients with COVID-19., PMID:39475087

Self-Tumor Antigens in Solid Tumors Turned into Vaccines by α-gal Micelle Immunotherapy., PMID:39458595

Serine protease RAYM_01812 (SspA) inhibits complement-mediated killing and monocyte chemotaxis and contributes to virulence of Riemerella anatipestifer in ducks., PMID:39450484

Serological Responses to Target Streptococcus pyogenes Vaccine Antigens in Patients With Proven Invasive β-Hemolytic Streptococcal Infections., PMID:39383256

Functional dependence following intensive care unit-treated sepsis: three-year follow-up results from the prospective Mid-German Sepsis Cohort (MSC)., PMID:39308983

Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587

Different Complement Activation Patterns Following C5 Cleavage in MOGAD and AQP4-IgG+NMOSD., PMID:39133885

Complete Description of the Three Pathways of the Complement System in a Series of 430 Patients with Rheumatoid Arthritis., PMID:39125933

Expression of the receptor for IgM (FcμR) by bovine neutrophils., PMID:39089639

Update on targeted treatments for ANCA-associated vasculitis., PMID:39089473

The safety and efficacy profile of eculizumab in myasthenic crisis: a prospective small case series., PMID:39072008

Structure of Designer Antibody-like Peptides Binding to the Human C5a with Potential to Modulate the C5a Receptor Signaling., PMID:39051153

Elucidating allergic reaction mechanisms in response to SARS-CoV-2 mRNA vaccination in adults., PMID:39033312

Avacopan for anti-neutrophil cytoplasm antibodies-associated vasculitis: a multicentre real-world study., PMID:39001799

Effect of Mild or Moderate Hepatic Impairment on the Pharmacokinetics of Avacopan, a Small-Molecule Complement C5a Receptor Antagonist, for the Treatment of Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis., PMID:38993026

Heterogeneity of treatment effect of vilobelimab in COVID-19: a secondary analysis of a randomised controlled trial., PMID:38943192

Elevated Complement Activation Fragments and C1q-Binding Circulating Immune Complexes in Varied Phases of Chikungunya Virus Infection., PMID:38913141

Serological Responses to Streptococcus pyogenes Vaccine Candidate Antigens Suggests That Streptococcus dysgalactiae Is the Predominant Cause of Lower Limb Cellulitis., PMID:38872850

FTY720 ameliorates experimental MPO-ANCA-associated vasculitis by regulating fatty acid oxidation via the neutrophil PPARα-CPT1a pathway., PMID:38837706

Crovalimab: First Approval., PMID:38740735

Kidney Failure in Pauci-immune Crescentic Glomerulonephritis: Rationale for Immunosuppression to Improve Kidney Outcome., PMID:38709420

Complement system is overactivated in patients with IgA nephropathy after COVID-19., PMID:38701960

Intravenous Ig Ameliorates Disease in a Murine Model of Anti-Laminin 332 Mucous Membrane Pemphigoid., PMID:38692406

A link between circulating immune complexes and acute kidney injury in human visceral leishmaniasis., PMID:38684845

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Mouse C5a Antibody (SAA0496) [RMB90001]
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