Catalog No.
RVV15602
Species reactivity
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Protein B5, Plaque-size/host range protein, PS/HR, B5R, VACWR187
Concentration
0.56 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q01227
Applications
Blocking
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
8AH8AL
Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques., PMID:38536937
The Global Monkeypox (Mpox) Outbreak: A Comprehensive Review., PMID:37376482
Proteomic assessment of humoral immune responses in smallpox vaccine recipients., PMID:34952760
Partial Deletion of Glycoprotein B5R Enhances Vaccinia Virus Neutralization Escape while Preserving Oncolytic Function., PMID:31236440
Protection of mice against the highly pathogenic VVIHD-J by DNA and fowlpox recombinant vaccines, administered by electroporation and intranasal routes, correlates with serum neutralizing activity., PMID:27637905
Vaccinia virus strain LC16m8 defective in the B5R gene keeps strong protection comparable to its parental strain Lister in immunodeficient mice., PMID:26241947
Vaccinia Virus LC16m8∆ as a Vaccine Vector for Clinical Applications., PMID:26344890
Systemically administered DNA and fowlpox recombinants expressing four vaccinia virus genes although immunogenic do not protect mice against the highly pathogenic IHD-J vaccinia strain., PMID:24050999
Effect of the deletion of genes encoding proteins of the extracellular virion form of vaccinia virus on vaccine immunogenicity and protective effectiveness in the mouse model., PMID:23785523
CD4+ T cells provide intermolecular help to generate robust antibody responses in vaccinia virus-vaccinated humans., PMID:23667112
L1R, A27L, A33R and B5R vaccinia virus genes expressed by fowlpox recombinants as putative novel orthopoxvirus vaccines., PMID:23578094
Protection of rabbits and immunodeficient mice against lethal poxvirus infections by human monoclonal antibodies., PMID:23133652
Safety and immunogenicity of LC16m8, an attenuated smallpox vaccine in vaccinia-naive adults., PMID:21921208
Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge., PMID:21885079
Single-shot immunization with recombinant adenovirus encoding vaccinia virus glycoprotein A27L is protective against a virulent respiratory poxvirus infection., PMID:20653083
Combination therapy of vaccinia virus infection with human anti-H3 and anti-B5 monoclonal antibodies in a small animal model., PMID:20587859
Protection against lethal vaccinia virus challenge by using an attenuated matrix protein mutant vesicular stomatitis virus vaccine vector expressing poxvirus antigens., PMID:20089648
Molecular smallpox vaccine delivered by alphavirus replicons elicits protective immunity in mice and non-human primates., PMID:19833247
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement., PMID:19019965
Targeting the vaccinia virus L1 protein to the cell surface enhances production of neutralizing antibodies., PMID:18485547
Differential antigen requirements for protection against systemic and intranasal vaccinia virus challenges in mice., PMID:18448519
Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge., PMID:18199639
Characterization and use of mammalian-expressed vaccinia virus extracellular membrane proteins for quantification of the humoral immune response to smallpox vaccines., PMID:17596428
B5-deficient vaccinia virus as a vaccine vector for the expression of a foreign antigen in vaccinia immune animals., PMID:17188733
Human T-cell responses to vaccinia virus envelope proteins., PMID:17005679
Subunit recombinant vaccine protects against monkeypox., PMID:16888017
Pathogenicity and immunogenicity in mice of vaccinia viruses mutated in the viral envelope proteins A33R and B5R., PMID:16406098
An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection., PMID:16140764
Role of genes that modulate host immune responses in the immunogenicity and pathogenicity of vaccinia virus., PMID:15858042
Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R., PMID:15858010
Differential efficacy of vaccinia virus envelope proteins administered by DNA immunisation in protection of BALB/c mice from a lethal intranasal poxvirus challenge., PMID:15308360
Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin., PMID:15246280
Smallpox DNA vaccine protects nonhuman primates against lethal monkeypox., PMID:15078924
Plasma membrane budding as an alternative release mechanism of the extracellular enveloped form of vaccinia virus from HeLa cells., PMID:12941903
Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates., PMID:12620810
Ultraviolet-irradiated vaccinia virus recombinants, exposing HIV-envelope on their outer membrane, induce antibodies against this antigen in rabbits., PMID:12479396
Immunization of rabbits with a modified vaccinia Ankara recombinant virus bearing the HIV envelope antigen on its outer membrane., PMID:12457978
Vaccinia virus intracellular movement is associated with microtubules and independent of actin tails., PMID:11689647
A mutational analysis of the vaccinia virus B5R protein., PMID:11297695
Antibody neutralization of the extracellular enveloped form of vaccinia virus., PMID:11162827
The immune response to vaccinia virus is significantly reduced after scarification with TK- recombinants as compared to wild-type virus., PMID:11155357
Neutralizing and protective antibodies directed against vaccinia virus envelope antigens., PMID:9927575
Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope., PMID:9636186
The envelope protein encoded by the A33R gene is required for formation of actin-containing microvilli and efficient cell-to-cell spread of vaccinia virus., PMID:9557708
Immunogenicity of recombinant vaccinia viruses that display the HIV type 1 envelope glycoprotein on the surface of infectious virions., PMID:9390748
Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination., PMID:8331727
Characterization of a vaccinia virus-encoded 42-kilodalton class I membrane glycoprotein component of the extracellular virus envelope., PMID:1433514
For research use only. Not for human or drug use.
