Catalog No.
VHB91201
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
PDGF-2, Proto-oncogene c-Sis, PDGF2, SIS, Platelet-derived growth factor B chain, PDGFB, Becaplermin, Platelet-derived growth factor beta polypeptide, Platelet-derived growth factor subunit B, PDGF subunit B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01127
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0072
Mechanical and biological properties of 3D-printed porous titanium scaffolds coated with composite growth factors., PMID:40426159
Synergistic Effects of Insulin-like Growth Factor-1 and Platelet-Derived Growth Factor-BB in Tendon Healing., PMID:40362278
PDGF-Releasing Hydrogels for Enhanced Proliferation of Human Nucleus Pulposus Cells., PMID:40344482
LONP1 facilitates pulmonary artery smooth muscle cell glycolytic reprogramming by degrading MPC1 in pulmonary hypertension., PMID:40332105
Enhancer-Associated LncRNA-ITGA2 Promotes Vascular Remodeling Through ITGA2., PMID:40321134
Vascular and metabolic responses to elevated circulating PDGF-BB in mice: A multiparametric MRI study., PMID:40308741
CDCP1 knockdown suppresses PDGFRβ/AKT pathway-mediated vascular smooth muscle cell proliferation by inhibiting PDGFRβ endocytosis., PMID:40256729
Multilayer Film with Bioactive and Antiadhesive Layers for Accelerated Tendon Regeneration., PMID:40195577
Biodegradable nano-immune agonist for enhanced immunotherapy of melanoma via the synergistic action of cuproptosis and cGAS-STING enhanced immune response., PMID:40120375
Combining the RCAS/tv-a retrovirus and CRISPR/Cas9 gene editing systems to generate primary mouse models of diffuse midline glioma., PMID:40056601
The Role of Luteolin in Inhibiting Prostaglandin-Endoperoxide Synthase 2 to Relieve Neointimal Hyperplasia in Arteriovenous Fistula., PMID:39960128
Improved tendon repair with optimized chemically modified mRNAs: Combined delivery of Pdgf-BB and IL-1Ra using injectable nanoparticles., PMID:39938707
Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB-Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer., PMID:39937190
Fabrication, characterization, and application of gelatin/alginate-based hydrogels incorporating selenium-doped deferoxamine-derived carbon quantum dots: In vitro and in vivo studies., PMID:39909275
Hsa_circ_0001304 promotes vascular neointimal hyperplasia accompanied by autophagy activation., PMID:39881153
Do the Shuffle: Expanding the Synthetic Biology Toolkit for Shufflon-like Recombination Systems., PMID:39869770
Semaphorin-4D signaling in recruiting dental stem cells for vascular stabilization., PMID:39865283
Convertible Hydrogel Injection Sequentially Regulates Diabetic Periodontitis., PMID:39792458
A polysaccharide from Glycyrrhiza uralensis attenuates myocardial fibrosis via modulating the MAPK/PI3K/AKT signaling pathway., PMID:39617235
LncRNA MEG3 aggravates acute pulmonary embolism-induced pulmonary arterial hypertension by regulating miR-34a-3p/DUSP1 axis., PMID:39551320
Biomimetic periosteum-bone scaffolds with codelivery of BMP-2 and PDGF-BB for skull repair., PMID:39505079
Quercetin regulates pulmonary vascular remodeling in pulmonary hypertension by downregulating TGF-β1-Smad2/3 pathway., PMID:39367342
lncRNA VELRP Modulates Pulmonary Arterial Smooth Muscle Cell Proliferation and Promotes Vascular Remodeling in Pulmonary Hypertension., PMID:39360410
The flavonoid hydroxygenkwanin reduces inflammation and neointimal formation., PMID:39299524
CXCL10 promotes melanoma angiogenesis and tumor growth., PMID:39268223
Restoration of ARA metabolic disorders in vascular smooth muscle cells alleviates intimal hyperplasia., PMID:39265882
β-sitosterol alleviates pulmonary arterial hypertension by altering smooth muscle cell phenotype and DNA damage/cGAS/STING signaling., PMID:39265206
MiRNA-132/212 encapsulated by adipose tissue-derived exosomes worsen atherosclerosis progression., PMID:39252021
Machine Learning-Driven Biomarker Discovery for Skeletal Complications in Type 1 Gaucher Disease Patients., PMID:39201273
ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration., PMID:39127448
HnRNPA1 Prevents Endothelial-to-mesenchymal Transition-induced VSMC Activation and Neointimal Hyperplasia in Vein Grafts., PMID:39046653
Inhibition effect of copper-bearing metals on arterial neointimal hyperplasia via the AKT/Nrf2/ARE pathway in vitro and in vivo., PMID:39027361
Inositol 1,4,5-Trisphosphate Receptors Regulate Vascular Smooth Muscle Cell Proliferation and Neointima Formation in Mice., PMID:39023067
Promotion of mature angiogenesis in ischemic stroke by Taohong Siwu decoction through glycolysis activation., PMID:38962303
AKAP1 alleviates VSMC phenotypic modulation and neointima formation by inhibiting Drp1-dependent mitochondrial fission., PMID:38850669
Kanglexin counters vascular smooth muscle cell dedifferentiation and associated arteriosclerosis through inhibiting PDGFR., PMID:38759316
Curcumol reduces lower limb arteriosclerosis in rats by inhibiting human arterial smooth muscle cell activity., PMID:38684457
Enhancing calvarial defects repair with PDGF-BB mimetic peptide hydrogels., PMID:38679161
Targeting deubiquitinase OTUB1 protects vascular smooth muscle cells in atherosclerosis by modulating PDGFRβ., PMID:38644399
Extracellular Vesicles of Patients on Peritoneal Dialysis Inhibit the TGF-β- and PDGF-B-Mediated Fibrotic Processes., PMID:38607044
A rhPDGF-BB/bovine type I collagen/β-TCP mixture for the treatment of critically sized non-union tibial defects: An in vivo study in rabbits., PMID:38598203
Senescent-like macrophages mediate angiogenesis for endplate sclerosis via IL-10 secretion in male mice., PMID:38580630
Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma., PMID:38566120
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis., PMID:38563133
CircTLK1: A novel regulator involved in VSMC phenotypic switching and the developmental process of atherosclerosis., PMID:38498343
Cathepsin K inhibition alleviates periodontal bone resorption by promoting type H vessel formation through PDGF-BB/PDGFR-β axis., PMID:38462960
Function of mast cell and bile-cholangiocarcinoma interplay in cholangiocarcinoma microenvironment., PMID:38458750
Isoxanthohumol reduces neointimal hyperplasia through the apelin/AKT pathway., PMID:38428686
Neonatal stress disrupts the glymphatic system development and increases the susceptibility to Parkinson's disease in later life., PMID:38421142
PDGFBB facilitates tumorigenesis and malignancy of lung adenocarcinoma associated with PI3K-AKT/MAPK signaling., PMID:38378786
For research use only. Not for human or drug use.
