Catalog No.
VHF46301
Species reactivity
Human
Host species
Human
Isotype
IgG4
Clonality
Monoclonal
Target
Glioblastoma-derived T-cell suppressor factor, TGF-beta-2, LAP, G-TSF, TGFB2, Cetermin, Transforming growth factor beta-2 proprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P61812
Applications
ELISA, FCM, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0070
Distinctive Amelogenesis Imperfecta in Loeys-Dietz Syndrome Type II., PMID:40261094
A SRC-slug-TGFβ2 signaling axis drives poor outcomes in triple-negative breast cancers., PMID:39327614
A tumor-promotional molecular axis CircMAPKBP1/miR-17-3p/TGFβ2 activates autophagy pathway to drive tongue squamous cell carcinoma cisplatin chemoresistance., PMID:39276917
RNA-seq transcriptomic profiling of TGF-β2-exposed human trabecular meshwork explants: Advancing insights beyond conventional cell culture models., PMID:39214330
Spatial transcriptomics of gastric cancer brain metastasis reveals atypical vasculature strategies with supportive immune profiles., PMID:39027914
Let‑7f‑5p Regulated by Hsa_circ_0000437 Ameliorates Bleomycin-Induced Skin Fibrosis., PMID:39004898
Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis., PMID:38563133
Role and action mechanisms of miR-149 and miR-31 in regulating function of pig cumulus cells and oocytes., PMID:38490113
Enzymatically Bioactive Nucleus Pulposus Matrix Hydrogel Microspheres for Exogenous Stem Cells Therapy and Endogenous Repair Strategy to Achieve Disc Regeneration., PMID:38145353
Exendin-4, a GLP-1 receptor agonist, suppresses diabetic retinopathy in vivo and in vitro., PMID:37920998
Anorexia Nervosa in vivo cytokine production: a systematic review., PMID:37769539
TCF12 Activates TGFB2 Expression to Promote the Malignant Progression of Melanoma., PMID:37760480
The hsa_circ_0004805/hsa_miR-149-5p/TGFB2 axis plays critical roles in the pathophysiology of diabetic retinopathy in vitro and in vivo., PMID:37567360
Let-7c-3p suppresses lens epithelial-mesenchymal transition by inhibiting cadherin-11 expression in fibrotic cataract., PMID:37171723
Single cell 'omic profiles of human aortic endothelial cells in vitro and human atherosclerotic lesions ex vivo reveals heterogeneity of endothelial subtype and response to activating perturbations., PMID:37066416
Coronary Artery Disease Risk Gene PRDM16 is Preferentially Expressed in Vascular Smooth Muscle Cells and a Potential Novel Regulator of Smooth Muscle Homeostasis., PMID:37066230
Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis., PMID:37023750
LncRNA TGFB2-OT1 Promotes Progression and Angiogenesis in Hepatocellular Carcinoma by Dephosphorylating β-Catenin., PMID:36941998
Scorpion venom peptide HsTx2 suppressed PTZ-induced seizures in mice via the circ_0001293/miR-8114/TGF-β2 axis., PMID:36457055
Active fractions of golden-flowered tea (Camellia nitidissima Chi) inhibit epidermal growth factor receptor mutated non-small cell lung cancer via multiple pathways and targets in vitro and in vivo., PMID:36386893
Oocyte-secreted factor TGFB2 enables mouse cumulus cell expansion in vitro., PMID:36128893
TGFB2-AS1 inhibits triple-negative breast cancer progression via interaction with SMARCA4 and regulating its targets TGFB2 and SOX2., PMID:36126099
Candidate genes for polycystic ovary syndrome are regulated by TGFβ in the bovine foetal ovary., PMID:35413103
Artesunate inhibits the development of PVR by suppressing the TGF-β/Smad signaling pathway., PMID:34822854
Capsaicin attenuates TGFβ2-induced epithelial-mesenchymal-transition in lens epithelial cells in vivo and in vitro., PMID:34798144
Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis., PMID:34706749
TGF-β2 and collagen play pivotal roles in the spheroid formation and anti-aging of human dermal papilla cells., PMID:34404755
TGF-β1 protein trap AVID200 beneficially affects hematopoiesis and bone marrow fibrosis in myelofibrosis., PMID:34383713
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis., PMID:34349032
β-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs., PMID:34246804
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β., PMID:34216686
Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury., PMID:34191077
Circular RNA circUbe2k promotes hepatic fibrosis via sponging miR-149-5p/TGF-β2 axis., PMID:33982351
A novel lncRNA TCLlnc1 promotes peripheral T cell lymphoma progression through acting as a modular scaffold of HNRNPD and YBX1 complexes., PMID:33767152
HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis., PMID:33563300
USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription., PMID:33558705
The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network., PMID:33214222
miR-200-3p suppresses cell proliferation and reduces apoptosis in diabetic retinopathy via blocking the TGF-β2/Smad pathway., PMID:33150936
Nanoscale microenvironment engineering based on layer-by-layer self-assembly to regulate hair follicle stem cell fate for regenerative medicine., PMID:33052240
LncRNA TGFB2-AS1 regulates lung adenocarcinoma progression via act as a sponge for miR-340-5p to target EDNRB expression., PMID:32774737
Alpha lipoic acid promotes development of hematopoietic progenitors derived from human embryonic stem cells by antagonizing ROS signals., PMID:32640500
Circ-SPECC1 modulates TGFβ2 and autophagy under oxidative stress by sponging miR-33a to promote hepatocellular carcinoma tumorigenesis., PMID:32627938
Biological effects of a new ultraviolet A1 prototype based on light-emitting diodes on the treatment of localized scleroderma., PMID:32592187
circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway., PMID:32019579
miR-324-5p inhibits gallbladder carcinoma cell metastatic behaviours by downregulation of transforming growth factor beta 2 expression., PMID:31858815
KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-β2 suppression., PMID:31538102
Therapeutic Targeting of TGFβ Ligands in Glioblastoma Using Novel Antisense Oligonucleotides Reduces the Growth of Experimental Gliomas., PMID:31530630
Overactivity or blockade of transforming growth factor-β each generate a specific ureter malformation., PMID:31400222
Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition., PMID:30971692
MiR-378a suppresses tenogenic differentiation and tendon repair by targeting at TGF-β2., PMID:30922407
For research use only. Not for human or drug use.
