Catalog No.
VVV20201
Species reactivity
Rotavirus A, Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) (RV-A)
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Outer capsid protein VP4, VP4, Hemagglutinin
Concentration
5.1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q2VE61, P11193, A0A385LUU7, A0A4D6QBC5
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0013
Immunoinformatics-driven design of a multi-epitope vaccine targeting neonatal rotavirus with focus on outer capsid proteins VP4 and VP7 and non structural proteins NSP2 and NSP5., PMID:40195509
Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis., PMID:36602365
The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling., PMID:30333172
Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice., PMID:18632867
Assembly of highly infectious rotavirus particles recoated with recombinant outer capsid proteins., PMID:16971442
Trypsin is associated with the rotavirus capsid and is activated by solubilization of outer capsid proteins., PMID:16227238
Selection of single-chain antibodies against the VP8* subunit of rotavirus VP4 outer capsid protein and their expression in Lactobacillus casei., PMID:15528568
Inhibition of rotavirus replication by a non-neutralizing, rotavirus VP6-specific IgA mAb., PMID:11994409
Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity., PMID:8600516
Cleavage of rotavirus VP4 in vivo., PMID:8601772
Molecular determinants of rotavirus virulence: localization of a potential virulence site in a murine rotavirus VP4., PMID:7924250
Characterization of two rotaviruses differing in their in vitro and in vivo virulence., PMID:8117825
Three-dimensional visualization of the rotavirus hemagglutinin structure., PMID:8395350
Recovery and characterization of a rotavirus outer capsid protein expressed in a recombinant insect cell system., PMID:8390880
Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence., PMID:8386262
Identification and partial characterization of a rhesus rotavirus binding glycoprotein on murine enterocytes., PMID:1649504