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Recombinant HIV-1 p24/Capsid protein p24 Protein, N-His-SUMO

Catalog #:   YVV19301 Specific References (86) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q70622
Protein length: Pro133-Leu363
Overview

Catalog No.

YVV19301

Expression system

E. coli

Species

Human immunodeficiency virus type 1 group M subtype B (isolate LW123) (HIV-1)

Protein length

Pro133-Leu363

Predicted molecular weight

38.11 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q70622

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Gag polyprotein, Pr55Gag, Capsid protein p24, gag, p24

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human immunodeficiency virus type 1/HIV-1 p24/Capsid protein p24 Protein
References

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents. PMID: 28077644

Standardization of a cytometric p24-capture bead-assay for the detection of main HIV-1 subtypes. PMID: 26808359

Changes in dynamic and static structures of the HIV-1 p24 capsid protein N-domain caused by amino-acid substitution are associated with its viral viability. PMID: 34523753

HIV-1 p24 but not proviral load is increased in the intestinal mucosa compared with the peripheral blood in HIV-infected patients. PMID: 9468362

HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function. PMID: 22807681

B cell epitopes of HIV type 1 p24 capsid protein: a reassessment. PMID: 8679307

Two types of nanoparticle-based bio-barcode amplification assays to detect HIV-1 p24 antigen. PMID: 22935171

Adaptation of the ultrasensitive HIV-1 p24 antigen assay to dried blood spot testing. PMID: 17146373

p24 as a predictor of mortality in a cohort of HIV-1-infected adults in rural Africa. PMID: 18545150

Frequency of cells positive for HIV-1 p24 antigen assessed by flow cytometry. PMID: 7909224

Cerebrospinal fluid HIV-1 p24 antigen and culture: sensitivity and specificity for AIDS-dementia complex. PMID: 8021661

Characterization of HIV-1 p24 self-association using analytical affinity chromatography. PMID: 1620693

Enhanced production of p24 Gag protein in HIV-1-infected rat cells fused with uninfected human cells. PMID: 17222823

Effects of tubeimoside-1 on HIV core protein p24 and cytopathogenesis in vitro. PMID: 8010099

Importin KPNA2 confers HIV-1 pre-integration complex nuclear import by interacting with the capsid protein. PMID: 35301060

Optimized virus disruption improves detection of HIV-1 p24 in particles and uncovers a p24 reactivity in patients with undetectable HIV-1 RNA under long-term HAART. PMID: 16789014

Performance of a quantitative human immunodeficiency virus type 1 p24 antigen assay on various HIV-1 subtypes for the follow-up of human immunodeficiency type 1 seropositive individuals. PMID: 14500124

Comparison of TaqMan real-time PCR and p24 Elisa for quantification of in vitro HIV-1 replication. PMID: 12505631

Chlamydia trachomatis Stimulation Enhances HIV-1 Susceptibility through the Modulation of a Member of the Macrophage Inflammatory Proteins. PMID: 34662561

Detection of p24 in HIV-1 infected cells embedded in LR White and Lowicryl K4M. PMID: 1917566

Specific immune response to human immunodeficiency virus (HIV)-1 in patients assessed through the production of interferon-gamma and interleukin-4 in HIV-1 p24-activated whole blood cultures: relationship with the viral load in plasma. PMID: 10404056

HIV-1 subtype O: epidemiology, pathogenesis, diagnosis, and perspectives of the evolution of HIV. PMID: 8800800

Immunophilins and HIV-1 infection. PMID: 12181673

HIV-1 capsid is involved in post-nuclear entry steps. PMID: 27107820

Anti-HIV-1 activity of phlorotannin derivative 8,4‴-dieckol from Korean brown alga Ecklonia cava. PMID: 25229850

Changes in HIV-1 Capsid Stability Induced by Common Cytotoxic-T-Lymphocyte-Driven Viral Sequence Mutations. PMID: 27279617

Apoptosis-induced activation of HIV-1 in latently infected cell lines. PMID: 25980942

Shortening of the window period in diagnosis of HIV-1 infection by simultaneous detection of p24 antigen and antibody IgG to p17 and reverse transcriptase in serum with ultrasensitive enzyme immunoassay. PMID: 8910647

In vitro anti-HIV-1 activity of fucoidan from Sargassum swartzii. PMID: 26472515

The therapeutic potential of RNA interference in controlling HIV-1 replication. PMID: 20124619

A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation. PMID: 2405486

HIV-1 diversity in an antiretroviral treatment naïve cohort from Bushbuckridge, Mpumalanga Province, South Africa. PMID: 25889106

Prevalence of human immunodeficiency virus type 1 p24 antigen in U.S. blood donors--an assessment of the efficacy of testing in donor screening. The HIV-Antigen Study Group. PMID: 2120589

Super-rapid quantitation of the production of HIV-1 harboring a luminescent peptide tag. PMID: 32719008

Assessment of antiretroviral therapy by plasma viral load testing: standard and ICD HIV-1 p24 antigen and viral RNA (QC-PCR) assays compared. PMID: 7552477

Construction and Characterization of Infectious Molecular Clones of HIV-1 CRF63_02A6. PMID: 31482716

HIV-1 infection facilitates Alzheimer's disease pathology in humanized APP knock-in immunodeficient mice., PMID:40309515

Inhibition of ALKBH5 demethylase of m6A pathway potentiates HIV-1 reactivation from latency., PMID:40296171

Subtype AD Recombinant HIV-1 Transmitted/Founder Viruses Are Less Sensitive to Type I Interferons than Subtype D., PMID:40284929

Ex vivo and in vivo HIV-1 latency reversal by "Mukungulu," a protein kinase C-activating African medicinal plant extract., PMID:40265896

Nanomechanical systems for the rapid detection of HIV-1 p24 antigen., PMID:40179694

Vitamin D Decreases Susceptibility of CD4+ T Cells to HIV Infection by Reducing AKT Phosphorylation and Glucose Uptake: A Bioinformatic and In Vitro Approach., PMID:40149968

Interleukin-27-polarized HIV-resistant M2 macrophages are a novel subtype of macrophages that express distinct antiviral gene profiles in individual cells: implication for the antiviral effect via different mechanisms in the individual cell-dependent manner., PMID:40129989

Association between HIV-1 Nef-mediated MHC-I downregulation and the maintenance of the replication-competent latent viral reservoir in individuals with virally suppressed HIV-1 in Uganda: an exploratory cohort study., PMID:40088911

The Human Milk Oligosaccharide Lacto-N-Fucopentaose III Conjugated to Dextran Inhibits HIV Replication in Primary Human Macrophages., PMID:40077760

Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1-infected CD4+ T cells by ADCC., PMID:40073240

Blood and tissue HIV-1 reservoirs display plasticity and lack of compartmentalization in virally suppressed people., PMID:40038305

The synthetic opioid fentanyl increases HIV replication in macrophages., PMID:40014575

Alternaria alternata (Fr) Keissl Crude Extract Inhibits HIV Subtypes and Integrase Drug-Resistant Strains at Different Stages of HIV Replication., PMID:40006004

HIV-1 Gag-protease-driven replicative capacity influences T-cell metabolism, cytokine induction, and viral cell-to-cell spread., PMID:39998252

Evaluation of a new human immunodeficiency virus antigen and antibody test using light-initiated chemiluminescent assay., PMID:39958931

Activating PKC-ε induces HIV expression with improved tolerability., PMID:39913544

Fourth-Generation HIV Rapid Tests: Enhanced Sensitivity and Reduced Diagnostic Window for HIV-1 Primary Infection Screening., PMID:39487652

IFI27 inhibits HIV-1 replication by degrading Gag protein through the ubiquitin-proteasome pathway., PMID:39475279

[The effect of sodium deoxyribonucleate with iron complex on the expression of surface markers of MT-4 cells infected with human immunodeficiency virus type 1 (HIV-1) (Retroviridae: Primate lentivirus group)]., PMID:39361925

Implications of accumulation of clonally expanded and senescent CD4+GNLY+ T cells in immunological non-responders of HIV-1 infection., PMID:39239709

HIV transcription persists in the brain of virally suppressed people with HIV., PMID:39116185

Performance evaluation of the new Access HIV Ag/Ab combo assay on the DxI 9000 Access Immunoassay Analyzer., PMID:39047323

Measuring Endoplasmic Reticulum Stress and Unfolded Protein Response in HIV-1 Infected T-Cells and Analyzing its Role in HIV-1 Replication., PMID:38949380

Limited HIV-associated neuropathologies and lack of immune activation in sub-saharan African individuals with late-stage subtype C HIV-1 infection., PMID:38943022

HIV-1 Structural Proteins or Cell-Signaling Factors? That Is the Question!, PMID:38920978

Rapid tests should be used with caution for HIV-1 primary infection screening., PMID:38907945

Genetic diversity in the partial sequence of the HIV-1 gag gene among people living with multidrug-resistant HIV-1 infection., PMID:38865573

Nanoparticle delivery of Tat synergizes with classical latency reversal agents to express HIV antigen targets., PMID:38829049

The EBI2 receptor is coexpressed with CCR5 in CD4 + T cells and boosts HIV-1 R5 replication., PMID:38770825

An Ultrasensitive p24 Assay to Measure HIV-1 in Diverse Biological Matrixes., PMID:38743239

Biochemical Detection of Capsid in the Nucleus During HIV-1 Infection., PMID:38743227

Phospho-Chitooligosaccharides below 1 kDa Inhibit HIV-1 Entry In Vitro., PMID:38666962

Sensitivity and specificity of the new Bio-Rad HIV screening test, Access HIV combo V2., PMID:38534108

HIV-1 Tat is present in the serum of people living with HIV-1 despite viral suppression., PMID:38447753

Low unspliced cell-associated HIV RNA in early treated adolescents living with HIV on long suppressive ART., PMID:38444847

The immunogenicity of p24 protein from HIV-1 virus is strongly supported and modulated by coupling with liposomes and mannan., PMID:38431385

Laboratory-based evaluation of the 4th-generation AlereTM HIV Combo rapid point-of-care test., PMID:38394120

Seronegative HIV-1 infection in a Japanese man presenting with Pneumocystis pneumonia: Analysis of long-term antibody response and literature review., PMID:38331251

Evaluation of the VioOne HIV profile supplemental assay., PMID:38206000

Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir., PMID:38110433

HIV-1 replication requires optimal activation of the unfolded protein response., PMID:37984889

Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice., PMID:37980794

In-house ELISA protocols for capsid p24 detection of diverse HIV isolates., PMID:37978551

Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography-Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study., PMID:37956323

NK cells from Men Who Have Sex with Men at high risk for HIV-1 infection exhibit higher effector capacity., PMID:37798386

Development of a Multiplex HIV/TB Diagnostic Assay Based on the Microarray Technology., PMID:37754128

hsa-miR-181-5p inhibits human immunodeficiency virus type 1 replication by downregulating DDX3X expression., PMID:37651885

Determination of Protein Monoclonal-Antibody Epitopes by a Combination of Structural Proteomics Methods., PMID:37526474

Nanodepots Encapsulating a Latency Reversing Agent and Broadly Neutralizing Antibody Enhance Natural Killer Cell Cytotoxicity Against an in vitro Model of Latent HIV., PMID:37520301

Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays., PMID:37414788

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant HIV-1 p24/Capsid protein p24 Protein, N-His-SUMO [YVV19301]
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